经宫颈羊水采集器：一种用于评估胎膜破裂患者羊水的新型医疗设备。
A transcervical amniotic fluid collector: a new medical device for the assessment of amniotic fluid in patients with ruptured membranes.
作者信息
Lee Seung Mi, Romero Roberto, Park Joong Shin, Chaemsaithong Piya, Jun Jong Kwan, Yoon Bo Hyun
出版信息
J Perinat Med. 2015 Jul;43(4):381-9. doi: 10.1515/jpm-2014-0276.
AIM
To describe a new device for the transcervical collection of amniotic fluid (AF) in patients with ruptured membranes, and to compare the concentration of proteins in fluid retrieved by transabdominal amniocentesis and the transcervical AF collector.
STUDY DESIGN
Paired AF samples were collected in patients with preterm prelabor rupture of membranes (PROM) (n=11) by transabdominal amniocentesis and with the transcervical AF collector (Yoon's AF Collector™). Three proteins known to have high concentrations in AF [α-fetoprotein (AFP), β-human chorionic gonadotrophin (β-hCG), and prolactin] were measured.
RESULTS
(1) There was a significant correlation between the concentrations of analytes in AF obtained by transabdominal amniocentesis and by the transcervical AF collector (r=0.94, P<0.001 for AFP; r=0.96, P<0.001 for β-hCG; r=0.72, P<0.05 for prolactin); (2) Bland-Altman plots showed no evidence of heteroscedasticity between transabdominal or transcervical AF concentrations of these markers.
CONCLUSIONS
There was a strong correlation between the concentrations of proteins in AF collected by amniocentesis or with the transcervical device.
目的
描述一种用于胎膜破裂患者经宫颈采集羊水（AF）的新装置，并比较经腹羊膜腔穿刺术和经宫颈羊水采集器所采集液体中的蛋白质浓度。
研究设计
对11例早产胎膜早破（PROM）患者，通过经腹羊膜腔穿刺术和经宫颈羊水采集器（尹氏羊水采集器™）采集配对的羊水样本。检测了三种已知在羊水中浓度较高的蛋白质[甲胎蛋白（AFP）、β-人绒毛膜促性腺激素（β-hCG）和催乳素]。
结果
（1）经腹羊膜腔穿刺术和经宫颈羊水采集器所采集羊水中分析物的浓度之间存在显著相关性（AFP：r = 0.94，P < 0.001；β-hCG：r = 0.96，P < 0.001；催乳素：r = 0.72，P < 0.05）；（2）布兰德-奥特曼图显示，这些标志物经腹或经宫颈羊水浓度之间无异方差证据。
结论
羊膜腔穿刺术或经宫颈装置所采集羊水中蛋白质浓度之间存在强相关性。
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