Hansi Navjyot, Thoua Nora, Carulli Maresa, Chakravarty Kuntal, Lal Simon, Smyth Anita, Herrick Ariane, Ogunbiyi Olagunju, Shaffer Jon, Mclaughlin John, Denton Christopher, Ong Voon, Emmanuel Anton V, Murray Charles D
Royal Free Hospital, London, UK.
Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-214-21. Epub 2014 Nov 5.
Systemic sclerosis is an autoimmune connective tissue disorder, which can be progressive with multisystem involvement. Guidance on the management of complications is based on a limited data set and practice amongst clinicians can vary. The UK Scleroderma study group set up several working groups to agree some consensus pathways for the management of specific complications. Approximately nine out of ten patients with systemic sclerosis will have involvement of the gastrointestinal system and in this review article we explore the management of these complications in a symptom-based approach. The algorithms are a useful tool for clinicians, which we hope, will be a point of reference and highlight the need for further research in these areas.
系统性硬化症是一种自身免疫性结缔组织疾病，可呈进行性发展并累及多个系统。关于并发症管理的指导基于有限的数据集，临床医生的实践也存在差异。英国硬皮病研究小组设立了几个工作组，以就特定并发症的管理达成一些共识路径。大约十分之九的系统性硬化症患者会累及胃肠道系统，在这篇综述文章中，我们以基于症状的方法探讨这些并发症的管理。这些算法对临床医生是一个有用的工具，我们希望它将成为一个参考点，并突出这些领域进一步研究的必要性。
