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多模式镇痛中Ⅰ和Ⅱ胸前神经阻滞用于乳腺癌手术:一项随机临床试验。

Pectoral nerves I and II blocks in multimodal analgesia for breast cancer surgery: a randomized clinical trial.

机构信息

From the Department of Anesthesia and Pain Management, National Cancer Institute, Cairo University, Cairo, Egypt.

出版信息

Reg Anesth Pain Med. 2015 Jan-Feb;40(1):68-74. doi: 10.1097/AAP.0000000000000163.

DOI:10.1097/AAP.0000000000000163
PMID:25376971
Abstract

BACKGROUND

The pectoral nerves (Pecs) block types I and II are novel techniques to block the pectoral, intercostobrachial, third to sixth intercostals, and the long thoracic nerves. They may provide good analgesia during and after breast surgery. Our study aimed to compare prospectively the quality of analgesia after modified radical mastectomy surgery using general anesthesia and Pecs blocks versus general anesthesia alone.

METHODS

One hundred twenty adult female patients scheduled for elective unilateral modified radical mastectomy under general anesthesia were randomly allocated to receive either general anesthesia plus Pecs block (Pecs group, n = 60) or general anesthesia alone (control group, n = 60).

RESULTS

Statistically significant lower visual analog scale pain scores were observed in the Pecs group than in the control group patients. Moreover, postoperative morphine consumption in the Pecs group was lower in the first 12 hours after surgery than in the control group. In addition, statistically significant lower intraoperative fentanyl consumption was observed in the Pecs group than in the control group. In the postanesthesia care unit, nausea and vomiting as well as sedation scores were lower in the Pecs group compared with the control group. Overall, postanesthesia care unit and hospital stays were shorter in the Pecs group than in the control group.

CONCLUSIONS

The combined Pecs I and II block is a simple, easy-to-learn technique that produces good analgesia for radical breast surgery.

摘要

背景

胸神经阻滞(Pecs)I 型和 II 型是阻滞胸肌、肋间臂神经、第 3 至 6 肋间神经和胸长神经的新技术。它们可能在乳房手术后提供良好的镇痛。我们的研究旨在前瞻性比较改良根治性乳房切除术在全身麻醉下联合 Pecs 阻滞与单纯全身麻醉的镇痛效果。

方法

120 名择期接受全身麻醉下单侧改良根治性乳房切除术的成年女性患者被随机分为接受全身麻醉加 Pecs 阻滞(Pecs 组,n = 60)或单纯全身麻醉(对照组,n = 60)。

结果

Pecs 组患者的视觉模拟评分疼痛明显低于对照组。此外,Pecs 组患者术后 12 小时内吗啡消耗量低于对照组。此外,Pecs 组术中芬太尼消耗量明显低于对照组。在麻醉后恢复室,Pecs 组的恶心、呕吐和镇静评分低于对照组。总体而言,Pecs 组的麻醉后恢复室和住院时间短于对照组。

结论

Pecs I 型和 II 型联合阻滞是一种简单、易于学习的技术,可为根治性乳房手术提供良好的镇痛。

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