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年龄匹配患者发育性髋关节脱位的内侧与前路切开复位术对比

Medial versus anterior open reduction for developmental hip dislocation in age-matched patients.

作者信息

Hoellwarth Jason S, Kim Young-Jo, Millis Michael B, Kasser James R, Zurakowski David, Matheney Travis H

机构信息

*University of Southern California Medical Center, Los Angeles, CA †Boston Children's Hospital, Boston, MA.

出版信息

J Pediatr Orthop. 2015 Jan;35(1):50-6. doi: 10.1097/BPO.0000000000000338.

Abstract

BACKGROUND

The difference between medial (MAOR) and anterior (AAOR) approaches for open reduction of developmental hip dysplasia in terms of risk for avascular necrosis (AVN) and need for further corrective surgery (FCS, femoral and/or acetabular osteotomy) is unclear. This study compared age-matched cohorts undergoing either MAOR or AAOR in terms of these 2 primary outcomes. Prognostic impact of presence of ossific nucleus at time of open reduction was also investigated.

METHODS

Institutional review board approval was obtained. Nineteen hips (14 patients) managed by MAOR were matched with 19 hips (18 patients) managed by AAOR based on age at operation (mean 6.0; range, 1.4 to 14.9 mo). Patients with neuromuscular conditions and known connective tissue disorders were excluded. Primary outcomes assessed at minimum 2 years' follow-up included radiographic evidence of AVN (Kalamchi and MacEwen) or requiring FCS.

RESULTS

MAOR and AAOR cohorts were similar regarding age at open reduction, sex, laterality, and follow-up duration. One hip in each group had AVN before open reduction thus were excluded from AVN analysis. At minimum 2 years postoperatively (mean 6.2; range, 1.8 to 11.7 y), 4/18 (22%) MAOR and 5/18 (28%) AAOR met the same criteria for AVN (P=1.0). No predictors of AVN could be identified by regression analysis. Presence of an ossific nucleus preoperatively was not a protective factor from AVN (P=0.27). FCS was required in 4/19 (21%) MAOR and 7/19 (37%) AAOR hips (P=0.48). However, 7/12 (54%) hips failing closed reduction required FCS compared with 4/26 (16%) hips without prior failed closed reduction (P=0.024). Cox regression analysis showed that patients who failed closed reduction had an annual risk of requiring FCS approximately 6 times that of patients without a history of failed closed reduction (hazard ratio=6.1; 95% CI, 1.5-24.4; P=0.009), independent of surgical approach (P=0.55) or length of follow-up (P=0.78).

CONCLUSIONS

In this study of age-matched patients undergoing either MAOR or AAOR, we found no association between surgical approach and risk of AVN or FCS. In addition, we identified no protective benefit of a preoperative ossific nucleus in terms of development of AVN. However, failing closed reduction was associated with a 6-fold increased annual risk of requiring FCS.

SIGNIFICANCE

To the best of our knowledge, this is the first study comparing these 2 surgical techniques in an age-matched manner. It further corroborates previous studies stating that there may be no difference in risk of AVN based on surgical approach or presence of ossific nucleus preoperatively.

LEVEL OF EVIDENCE

Level III-retrospective comparative study.

摘要

背景

在发育性髋关节发育不良切开复位手术中,内侧入路(MAOR)和前方入路(AAOR)在股骨头缺血性坏死(AVN)风险以及进一步矫正手术(FCS,股骨和/或髋臼截骨术)需求方面的差异尚不清楚。本研究比较了年龄匹配的接受MAOR或AAOR手术的队列在这两个主要结局方面的情况。同时还研究了切开复位时骨化核的存在对预后的影响。

方法

获得了机构审查委员会的批准。根据手术时年龄(平均6.0个月;范围1.4至14.9个月),将19例接受MAOR治疗的髋关节(14例患者)与19例接受AAOR治疗的髋关节(18例患者)进行匹配。排除患有神经肌肉疾病和已知结缔组织疾病的患者。在至少2年的随访中评估的主要结局包括AVN的影像学证据(Kalamchi和MacEwen标准)或需要进行FCS。

结果

MAOR组和AAOR组在切开复位时的年龄、性别、侧别和随访时间方面相似。每组各有1例髋关节在切开复位前发生AVN,因此被排除在AVN分析之外。术后至少2年(平均6.2年;范围1.8至11.7年),MAOR组18例中有4例(22%)、AAOR组18例中有5例(28%)符合相同的AVN标准(P = 1.)。通过回归分析未发现AVN的预测因素。术前存在骨化核并非AVN的保护因素(P = 0.27)。MAOR组19例中有4例(21%)、AAOR组19例中有7例(37%)的髋关节需要进行FCS(P = 0.48)。然而,闭合复位失败的12例髋关节中有7例(54%)需要进行FCS,而未经历过闭合复位失败的26例髋关节中有4例(16%)需要进行FCS(P = 0.024)。Cox回归分析显示,闭合复位失败的患者每年需要进行FCS的风险约为无闭合复位失败史患者的6倍(风险比 = 6.1;95%置信区间,1.5 - 24.4;P = 0.009),与手术入路(P = 0.55)或随访时间(P = 0.78)无关。

结论

在这项针对年龄匹配的接受MAOR或AAOR手术患者进行的研究中,我们发现手术入路与AVN风险或FCS需求之间无关联。此外,就AVN的发生而言,我们未发现术前骨化核对其有保护作用。然而,闭合复位失败与每年需要进行FCS的风险增加6倍相关。

意义

据我们所知,这是第一项以年龄匹配方式比较这两种手术技术(MAOR和AAOR)的研究。它进一步证实了先前的研究,即基于手术入路或术前骨化核的存在,AVN风险可能没有差异。

证据级别

III级——回顾性比较研究。

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