Department of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Aobaku, Sendai 980-8574, Japan.
Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
Nat Rev Neurol. 2014 Dec;10(12):679-81. doi: 10.1038/nrneurol.2014.216. Epub 2014 Nov 11.
Neuromyelitis optica spectrum disorders (NMOSD) can mimic multiple sclerosis (MS). Avoiding misdiagnosis is crucial, because some disease-modifying drugs for MS can aggravate NMOSD, causing blindness and paraplegia. A recent study reports that misdiagnosis of NMOSD as MS occasionally occurs, and that a two-step antibody assay could improve differential diagnosis.
视神经脊髓炎谱系疾病（NMOSD）可模拟多发性硬化症（MS）。避免误诊至关重要，因为一些用于 MS 的疾病修正药物可能会加重 NMOSD，导致失明和截瘫。最近的一项研究报告称，NMOSD 误诊为 MS 的情况偶尔会发生，两步抗体检测可改善鉴别诊断。
