Prijic Sergej M, Vukomanovic Vladislav A, Stajevic Mila S, Bjelakovic Bojko B, Zdravkovic Marija D, Sehic Igor N, Kosutic Jovan Lj
Cardiology Department, Mother and Child Health Institute of Serbia, R. Dakica St. 6-8, 11070, Belgrade, Serbia.
Pediatr Cardiol. 2015 Mar;36(3):616-24. doi: 10.1007/s00246-014-1056-6. Epub 2014 Nov 12.
Percutaneous balloon aortic valvoplasty (BAV) and surgical aortic valvotomy (SAV) are palliative procedures in patients with non-critical congenital valve stenosis. The aim of the study was to evaluate long-term BAV and SAV results after up to 24 years of follow-up. From 1987 to 2013, 74 consecutive interventions were performed in patients with aortic stenosis, and 62 were included in the study (39 BAVs and 23 SAVs). Age of BAV patients was 1.3 months to 17 years, and of SAV patients 1.2 months to 15 years. Although BAV patients were older, there was no difference between groups according to sex, valve function/morphology, and early/late follow-up results, with exception to hospitalization period. Significant pressure gradient reduction and aortic regurgitation increment were registered after procedures. Three patients did not survive early period after surgery. Follow-up period was 7.0 ± 5.4 and 9.0 ± 8.0 years after BAV and SAV, respectively (p = 0.242). Follow-up pressure gradient rose only in the BAV group, and was emphasized after 10-year-follow-up (p = 0.020). Significant aortic insufficiency progression was registered after 15 years of follow-up in both groups (p = 0.007 and p = 0.009, respectively). Mean reintervention-free survival was 12.0 years in the BAV and 14.5 years in the SAV group (p = 0.733), and mean survival without aortic valve replacement was 15.2 and 17.4 years, respectively (p = 0.877). BAV and SAV in patients with congenital aortic stenosis are very comparable in both early and late follow-up results.
经皮球囊主动脉瓣成形术(BAV)和外科主动脉瓣切开术(SAV)是治疗非重症先天性瓣膜狭窄患者的姑息性手术。本研究的目的是评估长达24年随访后的长期BAV和SAV结果。1987年至2013年,对主动脉狭窄患者连续进行了74次干预,其中62例纳入研究(39例BAV和23例SAV)。BAV患者年龄为1.3个月至17岁,SAV患者年龄为1.2个月至15岁。虽然BAV患者年龄较大,但除住院时间外,两组在性别、瓣膜功能/形态以及早期/晚期随访结果方面无差异。术后记录到显著的压力阶差降低和主动脉瓣反流增加。3例患者术后早期死亡。BAV和SAV后的随访期分别为7.0±5.4年和9.0±8.0年(p = 0.242)。随访压力阶差仅在BAV组升高,并在10年随访后更为明显(p = 0.020)。两组在随访15年后均记录到显著的主动脉瓣关闭不全进展(分别为p = 0.007和p = 0.009)。BAV组的平均无再次干预生存期为12.0年,SAV组为14.5年(p = 0.733),平均无主动脉瓣置换生存期分别为