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萨格勒布方案，一种狂犬病疫苗接种的简化肌肉注射程序。

Zagreb regimen, an abbreviated intramuscular schedule for rabies vaccination.

作者信息

Ren Jiangping, Yao Linong, Sun Jimin, Gong Zhenyu

机构信息

Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, People's Republic of China.

Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, People's Republic of China

出版信息

Clin Vaccine Immunol. 2015 Jan;22(1):1-5. doi: 10.1128/CVI.00531-14. Epub 2014 Nov 12.

DOI:10.1128/CVI.00531-14
PMID:25392012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4278924/
Abstract

The Zagreb regimen, an abbreviated intramuscular schedule for rabies vaccination, was developed by I. Vodopija and colleagues of the Zagreb Institute of Public Health in Croatia in the 1980s. It was recommended by WHO as one of the intramuscular (IM) schedules for rabies vaccination in 2010. We reviewed the literature on the immunogenicity, safety, economic burden, and compliance of the Zagreb 2-1-1 regimen. Compared to Essen, another IM schedule recommended by WHO, Zagreb has higher compliance, lower medical cost, and better immunogenicity at an early stage.

摘要

萨格勒布方案是一种用于狂犬病疫苗接种的简化肌肉注射程序，由克罗地亚萨格勒布公共卫生研究所的I. 沃多皮雅及其同事于20世纪80年代研发。2010年，世界卫生组织将其推荐为狂犬病疫苗肌肉注射程序之一。我们回顾了关于萨格勒布2-1-1方案的免疫原性、安全性、经济负担和依从性的文献。与世界卫生组织推荐的另一种肌肉注射程序埃森方案相比，萨格勒布方案具有更高的依从性、更低的医疗成本，且在早期具有更好的免疫原性。

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Comparison of safety and immunogenicity of purified chick embryo cell vaccine using Zagreb and Essen regimens in patients with category II exposure in China.中国II级暴露患者中使用萨格勒布和埃森方案的纯化鸡胚细胞疫苗的安全性和免疫原性比较。
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