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唇腭裂修复对颌面生长的影响。

The impact of cleft lip and palate repair on maxillofacial growth.

作者信息

Shi Bing, Losee Joseph E

机构信息

State Key Laboratory of Oral Diseases, Department of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

University Cleft-Craniofacial Center, Division of Pediatric Plastic Surgery, Children's Hospital of Pittsburgh, Pittsburgh, USA.

出版信息

Int J Oral Sci. 2015 Mar 23;7(1):14-7. doi: 10.1038/ijos.2014.59.

DOI:10.1038/ijos.2014.59
PMID:25394591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4817536/
Abstract

Surgical correction is central to current team-approached cleft treatment. Cleft surgeons are always concerned about the impact of their surgical maneuver on the growth of the maxilla. Hypoplastic maxilla, concaved mid-face and deformed dental arch have constantly been reported after cleft treatments. It is very hard to completely circumvent these postoperative complications by current surgical protocols. In this paper, we discussed the factors that inhibit the maxillofacial growth on cleft patients. These factors included pre-surgical intervention, the timing of cleft palate and alveolae repair, surgical design and treatment protocol. Also, we made a review about the influence on the maxillary growth in un-operated cleft patients. On the basis of previous researches, we can conclude that most of scholars express identity of views in these aspects: early palatoplasty lead to maxilla growth inhibition in all dimensions; secondary alveolar bone graft had no influence on maxilla sagittal growth; cleft lip repair inhibited maxilla sagittal length in patients with cleft lip and palate; Veau's pushback palatoplasty and Langenbeck's palatoplasty with relaxing incisions were most detrimental to growth; Furlow palatoplasty showed little detrimental effect on maxilla growth; timing of hard palate closure, instead of the sequence of hard or soft palate repair, determined the postoperative growth. Still, scholars hold controversial viewpoints in some issues, for example, un-operated clefts have normal growth potential or not, pre-surgical intervention and pharyngoplasty inhibited maxillofacial growth or not.

摘要

手术矫正是当前团队式腭裂治疗的核心。腭裂外科医生一直关注其手术操作对上颌骨生长的影响。腭裂治疗后,上颌骨发育不全、面中部凹陷和牙弓畸形屡有报道。目前的手术方案很难完全避免这些术后并发症。在本文中,我们讨论了影响腭裂患者颌面生长的因素。这些因素包括术前干预、腭裂和牙槽突修复的时机、手术设计和治疗方案。此外,我们还综述了未手术腭裂患者上颌骨生长的影响。基于以往的研究,我们可以得出结论,大多数学者在这些方面观点一致:早期腭裂修复术会导致上颌骨各维度生长受限;二期牙槽骨植骨对上颌骨矢状向生长无影响;唇裂修复术会抑制唇腭裂患者上颌骨矢状长度;Veau后推腭裂修复术和带松弛切口的Langenbeck腭裂修复术对生长最为不利;Furlow腭裂修复术对上颌骨生长的不利影响较小;硬腭关闭的时机而非硬腭或软腭修复的顺序决定术后生长。不过,学者们在一些问题上仍存在争议观点,例如,未手术腭裂是否具有正常生长潜力、术前干预和咽成形术是否抑制颌面生长。

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The impact of cleft lip and palate repair on maxillofacial growth.唇腭裂修复对颌面生长的影响。
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2
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本文引用的文献

1
The Craniofacial Morphology in Adult Patients with Unoperated Isolated Cleft Palate.成人未手术单纯腭裂患者的颅面形态。
Bone Res. 2013 Jun 28;1(2):195-200. doi: 10.4248/BR201302008. eCollection 2013 Jun.
2
The Children's Hospital of Philadelphia modification of the Furlow double-opposing Z-palatoplasty: 30-year experience and long-term speech outcomes.费城儿童医院改良的 Furlow 双瓣式腭裂修复术:30 年的经验和长期的语音效果。
Plast Reconstr Surg. 2013 Sep;132(3):613-622. doi: 10.1097/PRS.0b013e31829ad109.
3
Influence of pharyngeal flap surgery on maxillary outgrowth in cleft patients.腭裂患者咽瓣手术对上颌骨生长的影响。
Int J Oral Maxillofac Surg. 2013 Feb;42(2):192-7. doi: 10.1016/j.ijom.2012.09.022. Epub 2012 Nov 2.
4
[Clinical research of presurgical orthodontic treatment of complete cleft lip and palate infant].完全性唇腭裂婴儿术前正畸治疗的临床研究
Hua Xi Kou Qiang Yi Xue Za Zhi. 2011 Aug;29(4):396-9.
5
Two-stage palate repair with delayed hard palate closure is related to favorable maxillary growth in unilateral cleft lip and palate.采用两阶段腭裂修复术并延迟硬腭裂闭合与单侧唇腭裂患者上颌骨的有利生长有关。
Plast Reconstr Surg. 2010 May;125(5):1503-1510. doi: 10.1097/PRS.0b013e3181d5132a.
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Palatoplasty: evolution and controversies.腭裂修复术:发展历程与争议
Chang Gung Med J. 2008 Jul-Aug;31(4):335-45.
7
A cephalometric intercentre comparison of patients with unilateral cleft lip and palate at 5 and 10 years of age.5 岁和 10 岁单侧唇腭裂患者的头影测量中心间比较。
Eur J Orthod. 2010 Feb;32(1):24-7. doi: 10.1093/ejo/cjn051. Epub 2008 Sep 27.
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A comparative study of maxillary growth following rotation-advancement and triangular flap unilateral cleft lip repairs: an experimental study in rabbits.旋转推进与三角形皮瓣单侧唇裂修复术后上颌骨生长的比较研究:一项在兔身上的实验研究
Ann Plast Surg. 2007 Apr;58(4):434-40. doi: 10.1097/01.sap.0000237645.58470.24.
9
Presurgical nasoalveolar molding therapy for the treatment of unilateral cleft lip and palate: a preliminary study.术前鼻牙槽塑形治疗单侧唇腭裂:一项初步研究。
Cleft Palate Craniofac J. 2007 Jan;44(1):8-12. doi: 10.1597/06-009.
10
Comparison of craniofacial morphology in patients with unilateral cleft lip, alveolus and palate with and without secondary osteoplasty.单侧唇腭裂患者在进行和未进行二期骨成形术情况下的颅面形态比较。
J Craniomaxillofac Surg. 2006 Sep;34 Suppl 2:62-6. doi: 10.1016/S1010-5182(06)60014-0.