Abdin Edimansyah, Subramaniam Mythily, Vaingankar Janhavi Ajit, Luo Nan, Chong Siow Ann
Research Division, Institute of Mental Health, 10 Buangkok View, Singapore, Singapore,
Qual Life Res. 2015 Jun;24(6):1545-53. doi: 10.1007/s11136-014-0859-5. Epub 2014 Nov 14.
To provide norms for the EQ-5D index scores based on Singapore preference weights according to age, sex, ethnicity, and language version and compare the EQ-5D index scores for respondents with and without psychiatric disorders and chronic medical conditions.
The Singapore Mental Health Study was a cross-sectional epidemiological survey of a nationally representative sample of the resident (citizens and permanent residents) population in Singapore. The diagnoses of psychiatric disorders were established using the World Mental Health Composite International Diagnostic Interview version 3.0 (CIDI 3.0). Index scores were derived using the Singapore preference weights.
In general, the mean EQ-5D index score using Singapore preference weights decreased with increased age. The EQ-5D Malay version reported lower mean EQ-5D index than the English version. In multivariate analysis, the mean EQ-5D index for respondents with MDD, dysthymia, bipolar disorder, GAD, OCD, diabetes, hypertension, arthritis or rheumatism, neurological condition, stroke or major paralysis, heart attack, back problems, stomach ulcer, kidney failure, migraine headaches, and chronic lung disease was significantly lower than those without these conditions.
These findings support the use of the Singapore preference weights for EQ-5D valuations when measuring health-related quality of life and comparing the health burden of psychiatric and chronic physical conditions among adults in Singapore.
根据年龄、性别、种族和语言版本,基于新加坡偏好权重提供EQ-5D指数得分的规范,并比较有和没有精神疾病及慢性疾病的受访者的EQ-5D指数得分。
新加坡精神健康研究是一项对新加坡居民(公民和永久居民)全国代表性样本进行的横断面流行病学调查。使用世界精神健康综合国际诊断访谈第3.0版(CIDI 3.0)确定精神疾病的诊断。指数得分采用新加坡偏好权重得出。
总体而言,使用新加坡偏好权重的平均EQ-5D指数得分随年龄增长而降低。EQ-5D马来语版本报告的平均EQ-5D指数低于英语版本。在多变量分析中,患有重度抑郁症、心境恶劣障碍、双相情感障碍、广泛性焦虑障碍、强迫症、糖尿病、高血压、关节炎或风湿病、神经系统疾病、中风或严重瘫痪、心脏病发作、背部问题、胃溃疡、肾衰竭、偏头痛和慢性肺病的受访者的平均EQ-5D指数显著低于没有这些疾病的受访者。
这些发现支持在测量与健康相关的生活质量以及比较新加坡成年人中精神疾病和慢性身体疾病的健康负担时,使用新加坡偏好权重进行EQ-5D评估。