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澳大利亚昆士兰州 EQ-5D-3L 人群标准的比较,该标准使用了来自澳大利亚、英国和美国的效用值集进行估算。

A comparison of EQ-5D-3L population norms in Queensland, Australia, estimated using utility value sets from Australia, the UK and USA.

机构信息

Chief Health Officer Branch, Queensland Government Department of Health, Brisbane, Australia.

出版信息

Qual Life Res. 2014 Oct;23(8):2375-81. doi: 10.1007/s11136-014-0676-x. Epub 2014 Mar 28.

DOI:10.1007/s11136-014-0676-x
PMID:24676898
Abstract

PURPOSE

To provide population norms for the EQ-5D-3L by age and gender based on a representative adult sample in Queensland, Australia; to assess differences in health-related quality of life by applying the Australian, UK and USA value sets to these data; and to assess differences in utility scores for key preventive health indicators.

METHODS

A cross-sectional computer-assisted telephone interview survey (March-June 2011) with 5,555 adults. Respondents rated their impairment (none, moderate, severe problems) across five domains (mobility, self-care, usual activities, pain and discomfort, anxiety or depression) using the validated EQ-5D-3L health-related quality of life instrument. Utility score indexes were derived using the Australian, UK and USA value sets.

RESULTS

Forty per cent of adults reported pain and discomfort while 3% indicated problems with self-care. Approximately one in six had limitations with mobility, usual activities or anxiety or depression. The three value sets performed similarly in discriminating differences based on most characteristics, and clinically meaningful differences were seen for age, body weight, physical activity and daily smoking. There were no differences in utility scores for gender.

CONCLUSIONS

This is the first study to report general population findings for the Australian EQ-5D-3L value set. Overall, the Australian value set performed comparably with other value sets commonly used in the Australian population; however, differences were observed. Results will enable further refinement to health and economic studies in an Australian-specific context.

摘要

目的

基于澳大利亚昆士兰州的代表性成人样本,提供 EQ-5D-3L 的年龄和性别人群正常值;通过将澳大利亚、英国和美国的价值体系应用于这些数据,评估健康相关生活质量的差异;并评估主要预防健康指标的效用评分差异。

方法

2011 年 3 月至 6 月,采用横断面计算机辅助电话访谈调查对 5555 名成年人进行调查。受访者使用经过验证的 EQ-5D-3L 健康相关生活质量工具,在五个领域(行动能力、自理能力、日常活动、疼痛和不适、焦虑或抑郁)中对他们的受损程度(无、中度、严重问题)进行评分。使用澳大利亚、英国和美国的价值体系得出效用评分指数。

结果

40%的成年人报告有疼痛和不适,而 3%的人表示有自理问题。大约六分之一的人在行动能力、日常活动或焦虑或抑郁方面有局限性。三个价值体系在基于大多数特征的区分差异方面表现相似,在年龄、体重、身体活动和每日吸烟方面存在有临床意义的差异。性别对效用评分没有差异。

结论

这是第一项报告澳大利亚 EQ-5D-3L 价值体系的一般人群结果的研究。总体而言,澳大利亚价值体系与澳大利亚人群中常用的其他价值体系表现相当;然而,观察到了差异。结果将使在澳大利亚特定背景下的健康和经济研究得到进一步完善。

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