• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一种基于罗丹明的铜离子选择性探针的合成及其在细胞成像中的应用。

Synthesis of a Cu²⁺-selective probe derived from rhodamine and its application in cell imaging.

作者信息

Yu Chunwei, Wen Yingying, Zhang Jun

机构信息

Laboratory of Environmental Monitoring, School of Tropical and Laboratory Medicine, Hainan Medical University, Haikou 571199, China.

出版信息

Sensors (Basel). 2014 Nov 12;14(11):21375-84. doi: 10.3390/s141121375.

DOI:10.3390/s141121375
PMID:25397918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4279538/
Abstract

A new fluorescent probe P based on rhodamine for Cu2+ was synthesized and characterized. The new probe P showed high selectivity to Cu2+ over other tested metal ions. With optimal conditions, the proposed probe P worked in a wide linear range of 1.0 × 10(-6)-1.0 × 10(-5) M with a detection limit of 3.3 × 10(-7) M Cu2+ in ethanol-water solution (9:1, v:v, 20 mM HEPES, pH 7.0). Furthermore, it has been used for imaging of Cu2+ in living cells with satisfying results.

摘要

合成并表征了一种基于罗丹明的新型铜离子荧光探针P。新型探针P对铜离子的选择性高于其他测试金属离子。在最佳条件下，所提出的探针P在乙醇 - 水溶液（9:1，v:v，20 mM HEPES，pH 7.0）中，在1.0×10⁻⁶ - 1.0×10⁻⁵ M的宽线性范围内工作，铜离子检测限为3.3×10⁻⁷ M。此外，它已用于活细胞中铜离子的成像，结果令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/003d67454f82/sensors-14-21375f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/11a34262e435/sensors-14-21375f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/87534bf140ab/sensors-14-21375f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/0a83275e9e08/sensors-14-21375f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/9735ce7eeb7c/sensors-14-21375f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/4561258c04be/sensors-14-21375f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/eb3bbc4c8b5b/sensors-14-21375f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/8e0ba0e2e079/sensors-14-21375f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/e008d90d1406/sensors-14-21375f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/003d67454f82/sensors-14-21375f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/11a34262e435/sensors-14-21375f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/87534bf140ab/sensors-14-21375f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/0a83275e9e08/sensors-14-21375f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/9735ce7eeb7c/sensors-14-21375f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/4561258c04be/sensors-14-21375f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/eb3bbc4c8b5b/sensors-14-21375f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/8e0ba0e2e079/sensors-14-21375f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/e008d90d1406/sensors-14-21375f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0e8/4279538/003d67454f82/sensors-14-21375f9.jpg

相似文献

1
Synthesis of a Cu²⁺-selective probe derived from rhodamine and its application in cell imaging.一种基于罗丹明的铜离子选择性探针的合成及其在细胞成像中的应用。
Sensors (Basel). 2014 Nov 12;14(11):21375-84. doi: 10.3390/s141121375.
2
A highly selective fluorescent probe for Cu2+ based on rhodamine B derivative.一种基于罗丹明B衍生物的高选择性铜离子荧光探针。
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 24;124:416-22. doi: 10.1016/j.saa.2014.01.046. Epub 2014 Jan 22.
3
Rhodamine-based 'turn-on' fluorescent probe for Cu(II) and its fluorescence imaging in living cells.基于若丹明的“开-关”型荧光探针用于 Cu(II) 的检测及其在活细胞中的荧光成像。
Bioorg Med Chem Lett. 2013 May 15;23(10):2916-9. doi: 10.1016/j.bmcl.2013.03.052. Epub 2013 Mar 25.
4
A rhodamine based fluorescent probe for Hg2+ and its application to cellular imaging.基于罗丹明的汞离子荧光探针及其在细胞成像中的应用。
Spectrochim Acta A Mol Biomol Spectrosc. 2013 Apr;106:19-24. doi: 10.1016/j.saa.2012.12.079. Epub 2013 Jan 4.
5
A rhodamine-based "turn-on" fluorescent chemodosimeter for Cu2+ and its application in living cell imaging.基于罗丹明的“开启”型荧光铜离子化学传感器及其在活细胞成像中的应用。
J Inorg Biochem. 2011 Jun;105(6):800-5. doi: 10.1016/j.jinorgbio.2011.02.012. Epub 2011 Mar 22.
6
Development of a new rhodamine-based FRET platform and its application as a Cu2+ probe.一种基于罗丹明的新型荧光共振能量转移平台的开发及其作为铜离子探针的应用。
Org Biomol Chem. 2014 Jun 21;12(23):3944-9. doi: 10.1039/c4ob00131a.
7
A highly sensitive and selective fluorescent probe for trivalent aluminum ion based on rhodamine derivative in living cells.基于罗丹明衍生物的高灵敏度和选择性三价铝离子荧光探针在活细胞中的应用。
Anal Chim Acta. 2015 Aug 12;888:155-61. doi: 10.1016/j.aca.2015.07.033. Epub 2015 Aug 10.
8
A highly selective and sensitive probe for Cu2+ based on rhodamine-pyridazine conjugate and its application.一种基于罗丹明-哒嗪共轭物的高选择性、高灵敏度铜离子探针及其应用。
J Fluoresc. 2015 Jan;25(1):15-24. doi: 10.1007/s10895-014-1480-2. Epub 2014 Dec 10.
9
A dual functional probe for "turn-on" fluorescence response of Pb(2+) and colorimetric detection of Cu(2+) based on a rhodamine derivative in aqueous media.一种基于罗丹明衍生物的双功能探针，用于在水性介质中对Pb(2+)进行“开启”荧光响应以及对Cu(2+)进行比色检测。
Dalton Trans. 2015 Oct 21;44(39):17326-34. doi: 10.1039/c5dt02731d. Epub 2015 Sep 21.
10
A rhodamine-triazole fluorescent chemodosimeter for Cu detection and its application in bioimaging.一种用于检测铜的罗丹明-三唑荧光化学传感器及其在生物成像中的应用。
Luminescence. 2018 Feb;33(1):64-70. doi: 10.1002/bio.3373. Epub 2017 Jul 17.

引用本文的文献

1
Colorimetric and Fluorescent Sensing of Copper Ions in Water through o-Phenylenediamine-Derived Carbon Dots.基于邻苯二胺衍生碳点的水溶液中铜离子的比色和荧光传感检测。
Sensors (Basel). 2023 Mar 10;23(6):3029. doi: 10.3390/s23063029.
2
One-Step Green Synthesis of Water-Soluble Fluorescent Carbon Dots and Its Application in the Detection of Cu.水溶性荧光碳点的一步绿色合成及其在铜检测中的应用。
Nanomaterials (Basel). 2022 Mar 14;12(6):958. doi: 10.3390/nano12060958.
3
The Synthesis of a Coumarin Carbohydrazide Dinuclear Copper Complex Based Fluorescence Probe and Its Detection of Thiols.

本文引用的文献

1
Synthesis and characterization of a Mg2+-selective fluorescent probe.一种镁离子选择性荧光探针的合成与表征
Sensors (Basel). 2014 Jul 11;14(7):12560-7. doi: 10.3390/s140712560.
2
Recent progress in the development of near-infrared fluorescent probes for bioimaging applications.近红外荧光探针在生物成像应用中的最新进展。
Chem Soc Rev. 2014 Jan 7;43(1):16-29. doi: 10.1039/c3cs60271k. Epub 2013 Sep 19.
3
A fluorescent ratiometric chemodosimeter for Cu2+ based on TBET and its application in living cells.基于 TBET 的荧光比率型铜离子化学传感器及其在活细胞中的应用。
一种基于香豆素酰肼双核铜配合物的荧光探针的合成及其对硫醇的检测
PLoS One. 2016 Feb 12;11(2):e0148026. doi: 10.1371/journal.pone.0148026. eCollection 2016.
4
A pyridine-containing Cu²⁺-selective probe based on naphthalimide derivative.一种基于萘酰亚胺衍生物的含吡啶的Cu²⁺选择性探针。
Sensors (Basel). 2014 Dec 15;14(12):24146-55. doi: 10.3390/s141224146.
Org Lett. 2013 Feb 1;15(3):492-5. doi: 10.1021/ol3032889. Epub 2013 Jan 22.
4
NIR- and FRET-based sensing of Cu2+ and S2- in physiological conditions and in live cells.基于近红外和荧光共振能量转移的 Cu2+ 和 S2- 在生理条件下和活细胞中的检测。
Inorg Chem. 2013 Jan 18;52(2):743-52. doi: 10.1021/ic301872q. Epub 2013 Jan 9.
5
Naphthalimide appended rhodamine derivative: through bond energy transfer for sensing of Hg2+ ions.萘酰亚胺取代罗丹明衍生物：通过键能转移用于检测 Hg2+ 离子。
Org Lett. 2011 Mar 18;13(6):1422-5. doi: 10.1021/ol2001073. Epub 2011 Feb 16.
6
Highly sensitive and selective turn-on fluorescent and chromogenic probe for Cu2+ and ClO- based on a N-picolinyl rhodamine B-hydrazide derivative.基于 N-吡啶基罗丹明 B-酰腙衍生物的高灵敏和选择性 Cu2+ 和 ClO- 的荧光和比色探针。
Org Biomol Chem. 2011 Jan 21;9(2):432-7. doi: 10.1039/c0ob00411a. Epub 2010 Oct 28.
7
Highly sensitive and selective colorimetric and off-on fluorescent probe for Cu(2+) based on rhodamine derivative.基于罗丹明衍生物的高灵敏和选择性比色和关-开荧光探针用于 Cu(2+)检测。
Org Biomol Chem. 2010 Dec 7;8(23):5277-9. doi: 10.1039/c0ob00553c. Epub 2010 Oct 7.
8
Fluoro- and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens.用于溶液和生物样本中重金属离子检测的荧光和显色化学剂量计。
Chem Rev. 2010 Oct 13;110(10):6280-301. doi: 10.1021/cr100154p.
9
A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells.一种新的基于若丹明的铜离子化学传感器及其在活细胞中行为的研究。
Dalton Trans. 2010 Sep 14;39(34):7894-6. doi: 10.1039/c0dt00606h. Epub 2010 Jul 30.
10
Highly sensitive and selective colorimetric and off-on fluorescent chemosensor for Cu2+ in aqueous solution and living cells.用于水溶液和活细胞中 Cu2+ 的高灵敏和选择性比色和荧光化学传感器。
Anal Chem. 2009 Aug 15;81(16):7022-30. doi: 10.1021/ac901127n.