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腮腺多形性腺瘤的手术入路:一项15年的回顾性队列研究。

Surgical approach to parotid pleomorphic adenoma: a 15-year retrospective cohort study.

作者信息

Barca I, Cristofaro M G

机构信息

Department of Experimental and Clinical Medicine, Unit of Oral and Maxillofacial Surgery (Chairman: Prof.ssa M.G. Cristofaro) - "Magna Graecia" University, Viale Europa, 88100 Catanzaro, Italy.

出版信息

Br J Oral Maxillofac Surg. 2020 Jul;58(6):659-662. doi: 10.1016/j.bjoms.2020.03.020. Epub 2020 Apr 16.

DOI:10.1016/j.bjoms.2020.03.020
PMID:32307129
Abstract

Our aim was to investigate the clinical outcomes (recurrences, duration of follow-up, and effectiveness) after extracapsular dissection and superficial parotidectomy for pleomorphic adenoma of the parotid gland. We retrospectively studied 261 patients whose adenomas were treated at the Maxillofacial Unit of Magna Graecia University of Catanzaro between January 2003 and December 2015 and had been followed up for at least three years after either extracapsular dissection or superficial parotidectomy. The difference in recurrences and complications between the two techniques were measured by univariate analysis (Fisher's exact test). The level of significance was set at p ≤ 0.05. Of the 261 patients 125 were male (48%) and 136 female (52%), mean (range) age 47 (14-78) years. A total of 210 of the 261 patients had an extracapsular dissection (80%, 101 male and 109 female), and 51 had a superficial parotidectomy (24 male and 27 female). Postoperative complications were recorded in 48 of the 261 patients; complication rate was 10% in the extracapsular dissection group, and a third after superficial parotidectomy. There were more complications in the parotidectomy group (p=0.042). For pleomorphic adenomas located in the superficial portion of the parotid gland, extracapsular dissection is a viable alternative to traditional superficial parotidectomy in the hands of experienced parotid surgeons with regard to clinical outcomes, and it may be superior with regard to cost.

摘要

我们的目的是研究腮腺多形性腺瘤行囊外剥离术和腮腺浅叶切除术的临床结局(复发情况、随访时间和疗效)。我们回顾性研究了261例患者,这些患者的腺瘤于2003年1月至2015年12月在卡坦扎罗马格纳希腊大学颌面外科接受治疗,并且在接受囊外剥离术或腮腺浅叶切除术后至少随访了三年。通过单因素分析(Fisher精确检验)来衡量两种技术在复发和并发症方面的差异。显著性水平设定为p≤0.05。261例患者中,125例为男性(48%),136例为女性(52%),平均(范围)年龄47(14 - 78)岁。261例患者中共有210例行囊外剥离术(80%,男性101例,女性109例),51例行腮腺浅叶切除术(男性24例,女性27例)。261例患者中有48例记录了术后并发症;囊外剥离术组的并发症发生率为10%,腮腺浅叶切除术后为三分之一。腮腺切除术组的并发症更多(p = 0.042)。对于位于腮腺浅部的多形性腺瘤,在经验丰富的腮腺外科医生手中,就临床结局而言,囊外剥离术是传统腮腺浅叶切除术的一种可行替代方法,并且在成本方面可能更具优势。

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