Kim Bum Soo, Kwon Tae Gyun
Department of Urology, School of Medicine, Kyungpook National University, Daegu, South Korea,
Curr Urol Rep. 2015 Jan;16(1):467. doi: 10.1007/s11934-014-0467-5.
Urethral strictures may be caused by infections, trauma, or iatrogenic injuries. However, urethral reconstruction as a means of managing the long-segment urethral strictures can prove problematic. Various graft materials have been developed for use during urethroplasty. Although some graft techniques--including those using the buccal mucosa, bladder mucosa, colonic mucosa, and skin--have yielded good results, risks of surgical failure and donor site complications remain. Moreover, no graft material has yet been accepted as the clinical standard within the field of urology. This article provides a brief, updated review of both urethral strictures and clinically available graft materials for urethral reconstruction. In addition, we review previous studies involving autologous vein grafts for urethroplasty and discuss potential advances in the clinical use of these grafts.
尿道狭窄可能由感染、创伤或医源性损伤引起。然而，尿道重建作为治疗长段尿道狭窄的一种方法可能存在问题。在尿道成形术中已开发出各种移植材料。尽管一些移植技术——包括使用颊黏膜、膀胱黏膜、结肠黏膜和皮肤的技术——已取得了良好效果，但手术失败和供区并发症的风险仍然存在。此外，在泌尿外科领域，尚未有任何移植材料被接受为临床标准。本文简要介绍了尿道狭窄以及临床上可用于尿道重建的移植材料的最新情况。此外，我们回顾了以往涉及自体静脉移植用于尿道成形术的研究，并讨论了这些移植材料在临床应用中的潜在进展。
