Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA.
Sleep Breath. 2018 May;22(2):297-304. doi: 10.1007/s11325-017-1561-y. Epub 2017 Aug 29.
More than 50% of obstructive sleep apnea (OSA) patients have worsening of their OSA in the supine position (positional obstructive sleep apnea [POSA], commonly defined as supine to non-supine apnea hypopnea index (AHI) ratio of ≥ 2). Positional therapy (PT) aims to prevent patients from sleeping in the supine position. One of the major limiting factors to the routine use of PT in clinical practice is the lack of validated tools to measure compliance objectively. Furthermore, there are no universal guidelines to determine if PT will be effective as standalone or as adjunctive therapy. This paper assesses recent literature on PT demonstrating its effectiveness in management of POSA. It also outlines the proposed subclassification systems for POSA. Electronic literature review was done on EMBASE. Since the last review of PT by Ravesloot et al. (2012), ten studies were identified which demonstrate effectiveness of PT in POSA. We found three publications proposing different subclassification systems for POSA. There were three studies validating different compliance monitoring tools for PT. One study showed the cost benefits of incorporating PT into OSA management. Positional therapy is an effective treatment for POSA and progress has been made in development of tools for measuring compliance. Creating a subclassification of POSA may help develop targeted therapy for patients and determine its use as standalone or adjunct therapy. The integration of PT into POSA management may be cost-effective when compared to the use of CPAP alone.
超过 50%的阻塞性睡眠呼吸暂停(OSA)患者在仰卧位时会出现 OSA 恶化(位置性阻塞性睡眠呼吸暂停[POSA],通常定义为仰卧位与非仰卧位呼吸暂停低通气指数[AHI]比值≥2)。体位治疗(PT)旨在防止患者仰卧位睡眠。在临床实践中,常规使用 PT 的主要限制因素之一是缺乏客观测量依从性的经过验证的工具。此外,也没有普遍的指南来确定 PT 是否作为独立治疗或辅助治疗有效。本文评估了最近关于 PT 的文献,展示了其在 POSA 管理中的有效性。它还概述了 POSA 的拟议分类系统。在 EMBASE 上进行了电子文献综述。自 Ravesloot 等人(2012 年)对上一次 PT 审查以来,确定了十项研究表明 PT 在 POSA 中的有效性。我们发现有三篇出版物提出了不同的 POSA 分类系统。有三项研究验证了 PT 不同的依从性监测工具。一项研究表明将 PT 纳入 OSA 管理具有成本效益。体位治疗是 POSA 的有效治疗方法,在开发用于测量依从性的工具方面已经取得了进展。对 POSA 进行分类可能有助于为患者制定针对性治疗方法,并确定其作为独立或辅助治疗的用途。与单独使用 CPAP 相比,将 PT 纳入 POSA 管理可能具有成本效益。