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慢性溃疡性结肠炎和家族性腺瘤性息肉病行回肠贮袋手术后的功能及生活质量结果

Function and quality of life results after ileal pouch surgery for chronic ulcerative colitis and familial polyposis.

作者信息

Skarsgard E D, Atkinson K G, Bell G A, Pezim M E, Seal A M, Sharp F R

机构信息

Department of Surgery, University of British Columbia, Vancouver, Canada.

出版信息

Am J Surg. 1989 May;157(5):467-71. doi: 10.1016/0002-9610(89)90636-3.

Abstract

The aim of this study was to assess gastrointestinal function and quality of life, including occupational, social, and sexual function, in 75 patients who underwent pelvic pouch construction between November 1984 and May 1988 at our institution. Complications occurred in 45 percent of patients after pouch construction and in 17 percent after ileostomy closure. One patient died from sepsis caused by an anastomotic leak after ileostomy closure. The most common complication was a pouch-anal anastomotic stricture (22 percent), and the complication with the greatest potential morbidity was pouch-anal dehiscence (8 percent), which was highly predictive of pouch failure. Functional results were assessed by questionnaire during the 3-month period after ileostomy closure in all 58 patients who successfully attained intestinal continuity. A second assessment was performed at 15 +/- 11 months after ileostomy closure in 52 patients whose continuity had been restored for longer than 3 months. In an overall assessment, 94 percent of all patients with restored intestinal continuity (73 percent of entire patient group) rated the pouch as being superior to a permanent ileostomy and 92 percent (71 percent of entire group) would go through another pouch procedure. These results support the continued recommendation of this procedure as an acceptable alternative to proctocolectomy and permanent ileostomy in patients with ulcerative colitis or familial polyposis.

摘要

本研究旨在评估1984年11月至1988年5月在我院接受盆腔袋构建的75例患者的胃肠功能和生活质量,包括职业、社交和性功能。盆腔袋构建后45%的患者出现并发症,回肠造口关闭后17%的患者出现并发症。1例患者在回肠造口关闭后因吻合口漏导致败血症死亡。最常见的并发症是袋 - 肛门吻合口狭窄(22%),潜在发病率最高的并发症是袋 - 肛门裂开(8%),这对盆腔袋失败具有高度预测性。对所有成功实现肠道连续性的58例患者,在回肠造口关闭后的3个月内通过问卷调查评估功能结果。对52例肠道连续性恢复超过3个月的患者,在回肠造口关闭后15±11个月进行了第二次评估。在总体评估中,所有肠道连续性恢复的患者中有94%(占整个患者组的73%)认为盆腔袋优于永久性回肠造口,92%(占整个组的71%)愿意再次接受盆腔袋手术。这些结果支持继续推荐该手术,作为溃疡性结肠炎或家族性息肉病患者直肠结肠切除术和永久性回肠造口术的可接受替代方案。

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