Lopez Pila J M, Kopecka H, Vanden Berghe D
Institut für Wasser-, Boden- und Lufthygiene, Bundesgesundheitsamt, Berlin, F.R.G.
Antiviral Res. 1989 Feb;11(1):47-53. doi: 10.1016/0166-3542(89)90020-x.
Buffalo Green Monkey cells were infected with poliovirus-1 in the presence of 3-methylquercetin or guanidine, and the formation of positive- and negative-strand viral RNA was monitored using single-stranded RNA probes. Both 3-methylquercetin and guanidine prevented the formation of plus-strand as well as minus-strand viral RNA, although, due to the high multiplicity of infection used, a high number of genomic viral RNA was always present in the cells.
在3-甲基槲皮素或胍存在的情况下，用脊髓灰质炎病毒-1感染布法罗绿猴细胞，并使用单链RNA探针监测正链和负链病毒RNA的形成。尽管由于所用感染复数较高，细胞中总是存在大量基因组病毒RNA，但3-甲基槲皮素和胍均阻止了正链和负链病毒RNA的形成。
