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基于石墨烯量子点与竹红菌素A复合物的双功能二氧化硅纳米系统的多色成像及抗癌作用

Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.

作者信息

Zhou Lin, Zhou Lin, Ge Xuefeng, Zhou Jiahong, Wei Shaohua, Shen Jian

机构信息

College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, Wenyuan Road No. 1, Nanjing, China.

出版信息

Chem Commun (Camb). 2015;51(2):421-4. doi: 10.1039/c4cc06968d. Epub 2014 Nov 18.

DOI:10.1039/c4cc06968d
PMID:25407475
Abstract

An effective theranostic platform based on porous silica nanoparticles encapsulated with the complex of a photodynamic anticancer drug and graphene quantum dots (GQDs), with the bifunction of multicolor imaging and satisfactory photo-induced anticancer activity, was successfully designed and prepared for in vitro photodynamic therapy (PDT) of superficial cancer.

摘要

基于包裹有光动力抗癌药物与石墨烯量子点(GQDs)复合物的多孔二氧化硅纳米粒子,成功设计并制备了一种有效的诊疗平台,其具有多色成像和令人满意的光诱导抗癌活性的双重功能,用于浅表癌的体外光动力疗法(PDT)。

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