Han Min-Hee, Park Ki-Su, Park Seong-Hyun, Hwang Jeong-Hyun
Department of Neurosurgery, School of Medicine, Kyungpook National University, Daegu, Korea.
Brain Tumor Res Treat. 2014 Oct;2(2):81-6. doi: 10.14791/btrt.2014.2.2.81. Epub 2014 Oct 31.
Supratentorial extraventricular anaplastic ependymomas are extremely rare. We report the case of a 23-year-old male with a supratentorial extraventricular anaplastic ependymoma that presented with repeated intratumoral hemorrhage. The patient was diagnosed with an intracerebral hematoma in the left occipital lobe and underwent operation. The hematoma did not reveal tumor cells, but a new tumor grew in the same location 5 years later. Magnetic resonance imaging showed a tumor with intratumoral hemorrhage. The patient underwent the tumor resection. Intraoperative findings showed that the tumor had no continuity with the ventricle. Histopathological examinations confirmed an anaplastic ependymoma. The spinal evaluation was unremarkable, and radiotherapy was administered to the left occipital lobe. Four years later, the tumor recurred at the cervicomedullary junction and T8-T9 levels. This case demonstrates that anaplastic ependymomas should be included in the differential diagnoses of supratentorial extraventricular tumors presenting with repeated intratumoral hemorrhage.
幕上脑室外间变性室管膜瘤极为罕见。我们报告一例23岁男性幕上脑室外间变性室管膜瘤,该患者反复出现瘤内出血。患者最初被诊断为左枕叶脑内血肿并接受了手术。血肿中未发现肿瘤细胞,但5年后在同一部位长出了新肿瘤。磁共振成像显示为伴有瘤内出血的肿瘤。患者接受了肿瘤切除术。术中发现肿瘤与脑室无连续性。组织病理学检查确诊为间变性室管膜瘤。脊髓评估未见异常,对左枕叶进行了放射治疗。4年后,肿瘤在颈髓交界处和T8 - T9水平复发。该病例表明,间变性室管膜瘤应纳入幕上脑室外肿瘤伴反复瘤内出血的鉴别诊断中。