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代谢性骨病的最新进展:从颌骨角度看

Recent developments in metabolic bone diseases: a gnathic perspective.

作者信息

Raubenheimer Erich J, Noffke Claudia E, Hendrik Hilde D

机构信息

Pathology, School of Oral Health Sciences, Medunsa Campus, University of Limpopo, Pretoria, 0204, South Africa,

出版信息

Head Neck Pathol. 2014 Dec;8(4):475-81. doi: 10.1007/s12105-014-0580-2. Epub 2014 Nov 20.

Abstract

Metabolic bone diseases often are asymptomatic and progress sub clinically. Many patients present at a late stage with catastrophic skeletal and extra skeletal complications. In this article, we provide an overview of normal bone remodeling and a synopsis of recent developments in the following conditions: osteoporosis, rickets/osteomalacia, endocrine-induced bone disease, chronic kidney disease-mineral bone disorder and Paget's disease of bone. Our discussion will emphasize the clinical and microscopic manifestations of these diseases in the jaws.

摘要

代谢性骨病通常无症状,呈亚临床进展。许多患者在疾病晚期出现严重的骨骼及骨骼外并发症。在本文中,我们概述了正常骨重塑,并简述了以下疾病的最新进展:骨质疏松症、佝偻病/骨软化症、内分泌性骨病、慢性肾脏病-矿物质和骨异常以及佩吉特骨病。我们的讨论将重点关注这些疾病在颌骨的临床和微观表现。

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本文引用的文献

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Pathobiology of Paget's Disease of Bone.骨佩吉特病的病理生物学
J Bone Metab. 2014 May;21(2):85-98. doi: 10.11005/jbm.2014.21.2.85. Epub 2014 May 31.
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Paget's disease of bone: clinical review and update.骨 Paget 病:临床综述与更新。
J Clin Pathol. 2013 Nov;66(11):924-7. doi: 10.1136/jclinpath-2013-201688. Epub 2013 Sep 16.

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