Raubenheimer Erich J, Noffke Claudia E, Hendrik Hilde D
Pathology, School of Oral Health Sciences, Medunsa Campus, University of Limpopo, Pretoria, 0204, South Africa,
Head Neck Pathol. 2014 Dec;8(4):475-81. doi: 10.1007/s12105-014-0580-2. Epub 2014 Nov 20.
Metabolic bone diseases often are asymptomatic and progress sub clinically. Many patients present at a late stage with catastrophic skeletal and extra skeletal complications. In this article, we provide an overview of normal bone remodeling and a synopsis of recent developments in the following conditions: osteoporosis, rickets/osteomalacia, endocrine-induced bone disease, chronic kidney disease-mineral bone disorder and Paget's disease of bone. Our discussion will emphasize the clinical and microscopic manifestations of these diseases in the jaws.
代谢性骨病通常无症状，呈亚临床进展。许多患者在疾病晚期出现严重的骨骼及骨骼外并发症。在本文中，我们概述了正常骨重塑，并简述了以下疾病的最新进展：骨质疏松症、佝偻病/骨软化症、内分泌性骨病、慢性肾脏病-矿物质和骨异常以及佩吉特骨病。我们的讨论将重点关注这些疾病在颌骨的临床和微观表现。
