Buck Institute for Research on Aging, Novato, CA USA.
Penn Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology and Department of Genetics and Department of Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Cell. 2014 Nov 6;159(4):709-13. doi: 10.1016/j.cell.2014.10.039.
Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk factor for a majority of chronic diseases driving both morbidity and mortality, it is critical to expand geroscience research directed at extending human healthspan.
哺乳动物的衰老可以通过遗传、饮食和药物方法来延缓。鉴于老年人口数量的急剧增加,以及衰老是导致大多数导致发病率和死亡率的慢性疾病的最大风险因素,扩大旨在延长人类健康寿命的衰老科学研究至关重要。