中药治疗流感的疗效：随机对照试验的系统评价和荟萃分析。
Traditional Chinese medicine for the treatment of influenza: a systematic review and meta-analysis of randomized controlled trials.
出版信息
J Tradit Chin Med. 2014 Oct;34(5):527-31. doi: 10.1016/s0254-6272(15)30057-1.
OBJECTIVE
To justify the clinical use of Traditional Chinese Medicine (TCM) in the treatment of influenza.
METHODS
MEDLINE, EMBASE, Chinese Biomedical Literature Database, China National Knowledgeln-frastructure Database, China Science and Technology Journal Database, Wanfang Database and the Cochrane Database of Systematic Reviews were searched from the date of inception until January 1, 2013, for the literature on treatment of influenza with TCM.
RESULTS
A total of 7 randomized controlled trials were identified and reviewed. Of these trials, 2 compared a (modified) prescription of TCM with oseltacmivir and 5 compared a patent traditional Chinese drug with oseltamivir. Based on the Meta-analysis, compared to oseltamivir, the (modified) prescription had similar effect in defervescence [WMD = 5.66, 95% CI (- 32.02, 43.35), P = 0.77] and viral sheddingWMD = - 6.21, 95% CI (- 84.19, 71.76), P = 0.88], and the patent traditional Chinese drug also had similar effect in viral shedding [WMD = - 0.24, 95% CI (- 4.79, 4.31), P = 0.92] but more effective in defervescence [WMD = - 4.65, 95%CI (- 8.91, - 0.38),P = 0.03].
CONCLUSION
TCM has potential positive effects in the treatment of influenza.
目的
论证中药治疗流感的临床应用。
方法
检索 MEDLINE、EMBASE、中国生物医学文献数据库、中国国家知识基础设施数据库、中国科技期刊数据库、万方数据库和 Cochrane 系统评价数据库，时间截至 2013 年 1 月 1 日，以获取中药治疗流感的文献。
结果
共纳入 7 项随机对照试验进行评价。其中 2 项试验比较了中药（加减）方与奥司他韦的疗效，5 项试验比较了专利中药与奥司他韦的疗效。Meta 分析结果显示，与奥司他韦相比，中药（加减）方在退热方面疗效相当[WMD = 5.66，95%CI（-32.02，43.35），P = 0.77]，在病毒脱落方面疗效相当[WMD = -6.21，95%CI（-84.19，71.76），P = 0.88]，专利中药在病毒脱落方面疗效相当[WMD = -0.24，95%CI（-4.79，4.31），P = 0.92]，但在退热方面更有效[WMD = -4.65，95%CI（-8.91，-0.38），P = 0.03]。
结论
中药治疗流感可能具有积极作用。
Zotero 插件