Yazdanshenas Hamed, Bazargan Mohsen, Orum Gail, Loni Leila, Mahabadi Navid, Husaini Baqar
Ethn Dis. 2014 Autumn;24(4):431-7.
Hypertension among African Americans is higher compared to Whites and has an early onset, greater severity, and is associated with more organ damage. We examined whether pharmaceutical treatment of hypertension among underserved African American elderly is consistent with the current treatment guidelines and whether treatment variations occur due to existing co-morbidities among the hypertensive.
Our study surveyed 400 African Americans, aged ≥ 65 years, recruited from 16 predominantly African American churches located in South Los Angeles. The study used face-to-face interviews which documented type, frequency, and dosage of all medications used by participants. Label information of each drug was recorded.
Our data indicate: 1) 29% were on one anti-hypertensive medication; 60% were taking 2-3 medications; and 9% were on four classes of anti-hypertensive medication; 2) among the elderly taking a combination of two or more drugs, ACE or ARB was used 76% in combination of agents, diuretics 60%, calcium channel blockers 63%, and beta-blocker 61%; and 3) 26% of the elderly were taking ≥ 3 medications including a diuretic.
Treatment of hypertension appears to be inconsistent with the prevailing treatment guidelines for nearly one-third of the aged African Americans. Further investigation is needed to determine why a significant number of individuals from this under-served population are not receiving care based on established clinical guidelines.
非裔美国人的高血压发病率高于白人,且发病早、病情严重,与更多器官损害相关。我们研究了在医疗服务不足的非裔美国老年人中,高血压药物治疗是否符合当前治疗指南,以及高血压患者中是否因现有合并症而出现治疗差异。
我们的研究对400名年龄≥65岁的非裔美国人进行了调查,这些人是从位于洛杉矶南部的16个主要为非裔美国人的教会招募的。该研究采用面对面访谈,记录参与者使用的所有药物的类型、频率和剂量。记录了每种药物的标签信息。
我们的数据表明:1)29%的人服用一种抗高血压药物;60%的人服用2 - 3种药物;9%的人服用四类抗高血压药物;2)在服用两种或更多药物组合的老年人中,ACE或ARB与其他药物联合使用的占76%,利尿剂占60%,钙通道阻滞剂占63%,β受体阻滞剂占61%;3)26%的老年人服用≥3种药物,包括一种利尿剂。
近三分之一的老年非裔美国人的高血压治疗似乎与现行治疗指南不一致。需要进一步调查,以确定为什么这一服务不足人群中有相当数量的人没有按照既定的临床指南接受治疗。