William T, Menon J
Queen Elizabeth Hospital, Dept of Medicine, Infectious Disease Unit, Kota Kinabalu, Sabah, Malaysia.
Queen Elizabeth Hospital, Dept of Medicine, Kota Kinabalu, Sabah, Malaysia.
Med J Malaysia. 2014 Aug;69 Suppl A:82-7.
One hundred and thirteen articles related to Malaria were found in a search through a database dedicated to indexing all original data relevant to medicine published in Malaysia between the years 2000-2013. Thirty eight articles were selected and reviewed on the basis of clinical relevance and future research implications. The epidemiology of malaria has undergone a significant change over the last decade with P. knowlesi, formerly a relatively unknown simian parasite rapidly becoming the most predominant malaria species to infect humans in Malaysia. The epidemiology, clinical features, diagnostic methods and treatment for P. knowlesi infection are described in these studies. In Malaysia, imported malaria from foreigners also poses a challenge. In view of these changes, new strategies on malaria control need to be devised and implemented, and treatment regimens need to be redefined to help Malaysia achieve the goal of malaria elimination by the year 2020.
通过一个专门索引2000年至2013年间在马来西亚发表的所有与医学相关的原始数据的数据库进行检索,发现了113篇与疟疾相关的文章。基于临床相关性和未来研究意义,挑选并审阅了38篇文章。在过去十年中,疟疾的流行病学发生了重大变化,诺氏疟原虫,一种以前相对不为人知的猿类寄生虫,迅速成为马来西亚感染人类的最主要疟原虫种类。这些研究描述了诺氏疟原虫感染的流行病学、临床特征、诊断方法和治疗方法。在马来西亚,来自外国人的输入性疟疾也构成了挑战。鉴于这些变化,需要制定和实施新的疟疾控制策略,并重新定义治疗方案,以帮助马来西亚实现到2020年消除疟疾的目标。