Cao Kaiwu, Xu Jinsong, Sun Hanjun, Li Ping, Li Juxiang, Cheng Xiaoshu, Su Hai
Department of Cardiology, Second Affiliated Hospital of Nanchang University, Nanchang, China.
Department of Cardiology, Second Affiliated Hospital of Nanchang University, Nanchang, China.
J Am Soc Hypertens. 2014 Oct;8(10):693-8. doi: 10.1016/j.jash.2014.07.030. Epub 2014 Jul 21.
The purpose of this study was to investigate whether ankle-arm blood pressure (BP) difference (An-a) and ankle-brachial index (ABI) are consistent in treated hypertensive patients with obvious BP variation. This study enrolled 414 hypertensive patients (200 males; mean age, 61.3 ± 13.3 years) admitted to our hospital. BP of four limbs was simultaneously measured using four automatic BP measurement devices on the day of admission, and three and six day after admission. The An-a differences on systolic BP (SBP), diastolic BP (DBP), mean artery pressure (MAP), and pulse pressure (PP) in both sides were calculated, respectively. The relative decrease amplitude (RDA) of BP was calculated using the formula: RDA = (BP1 - BPn)/BP1. The ABI of the right side was calculated. From the first to the third measurement, arm SBP and DBP levels of both arms significantly decreased (right arm: SBP: 163.7 ± 18.4, 147.7 ± 15.3 vs. 135.4 ± 11.7 mm Hg; P < .05; DBP: 86.6 ± 13.4, 79.9 ± 11.6 vs. 74.5 ± 9.6 mm Hg; P < .05); at the same time, the ankle SBP (right ankle: 182.1 ± 22.1, 147.7 ± 15.3 vs. 153.4 ± 16.6 mm Hg; P < .05) and DBP (84.8 ± 13.4, 79.9 ± 11.6 vs. 75.8 ± 9.8 mm Hg; P < .05) of both sides also significantly decreased. The mean An-a of three measurements of both sides was consistent at the levels of about 20 mm Hg on SBP and PP, 7 mm Hg on MAP, and 0 mm Hg on DBP. However, sABI gradually increased from the first to the third measurement.In treated hypertensive patients, the An-a differences on SBP, DBP, PP, and MAP are generally consistent, but sABI is associated with underlying SBP levels.
本研究旨在调查在血压有明显波动的接受治疗的高血压患者中，踝臂血压差（An-a）与踝臂指数（ABI）是否一致。本研究纳入了我院收治的414例高血压患者（男性200例；平均年龄61.3±13.3岁）。在入院当天、入院后第3天和第6天，使用四台自动血压测量设备同时测量四肢血压。分别计算两侧收缩压（SBP）、舒张压（DBP）、平均动脉压（MAP）和脉压（PP）的An-a差值。血压的相对下降幅度（RDA）采用公式计算：RDA =（BP1 - BPn）/BP1。计算右侧的ABI。从第一次测量到第三次测量，双臂的上臂SBP和DBP水平均显著下降（右臂：SBP：163.7±18.4、147.7±15.3对比135.4±11.7 mmHg；P<.05；DBP：86.6±13.4、79.9±11.6对比74.5±9.6 mmHg；P<.05）；同时，两侧的踝部SBP（右踝：182.1±22.1、147.7±15.3对比153.4±16.6 mmHg；P<.05）和DBP（84.8±13.4、79.9±11.6对比75.8±9.8 mmHg；P<.05）也显著下降。两侧三次测量的平均An-a在SBP和PP水平约为20 mmHg、MAP水平约为7 mmHg、DBP水平约为0 mmHg时是一致的。然而，从第一次测量到第三次测量，sABI逐渐升高。在接受治疗的高血压患者中，SBP、DBP、PP和MAP的An-a差值通常是一致的，但sABI与基础SBP水平相关。
