Mamidala Madhu P, Kalikiri Mahesh K, Praveen Kumar P T V, Rajesh N, Vallamkonda OmSai R, Rajesh Vidya
Department of Biological Sciences, Birla Institute of Technology and Science, Hyderabad, India.
Autism Res. 2015 Apr;8(2):224-8. doi: 10.1002/aur.1431. Epub 2014 Nov 26.
Autism Spectrum Disorder (ASD) has both genetic and environmental factors in its etiology. The risk for many disorders is increased by consanguinity, but it is not known whether it increases the risk for ASD. Our study from large population in India concludes that consanguinity increases the risk for ASD with an odds ratio of 3.22.
自闭症谱系障碍（ASD）的病因既有遗传因素也有环境因素。近亲结婚会增加许多疾病的患病风险，但尚不清楚其是否会增加患ASD的风险。我们来自印度大量人群的研究得出结论，近亲结婚会使患ASD的风险增加，优势比为3.22。
