Vega-Alvarez M, Garbarg-Chenon A, Goulin J, Nicolas J C, Bricout F
Laboratoire de Virologie, Hôpital Trousseau, Paris, France.
Pathol Biol (Paris). 1989 Mar;37(3):195-8.
Cytomegalovirus is frequently isolated from immunosuppressed patients or from patients with acquired immunodeficiency syndrome. Twelve patients were studied for several months. In 7 patients more than 1 Cytomegalovirus was isolated; in one of these patients three viruses were isolated, two of them show small differences in their migration pattern and the third seems to be a different strain after restriction analysis of CMV genome. This could reflect variation in the genome of the CMV virus as it has been already shown for viruses from other families in immunocompromised patients and shows the occurrence of multiple strains infection in a single patient.
巨细胞病毒经常从免疫抑制患者或获得性免疫缺陷综合征患者中分离出来。对12名患者进行了数月的研究。在7名患者中分离出了不止一种巨细胞病毒；其中一名患者分离出了三种病毒，其中两种在迁移模式上有微小差异，第三种在对巨细胞病毒基因组进行限制性分析后似乎是不同的毒株。这可能反映了巨细胞病毒基因组的变异，正如在免疫受损患者中对其他病毒家族的病毒所显示的那样，并且表明在单个患者中发生了多毒株感染。
