Niedergethmann M, Nephuth O, Hasenberg T
Alfried Krupp Krankenhaus, Klinik für Allgemein- und Viszeralchirurgie, Alfried-Krupp-Str. 21, 45131, Essen, Deutschland,
Chirurg. 2014 Dec;85(12):1123-31; quiz 1132-3. doi: 10.1007/s00104-014-2871-2.
Chronic pancreatitis can lead to intractable pain, pancreatic duct obstruction, duodenal stenosis and vascular compression syndromes. Surgical interventions can effectively treat these symptoms. Endoscopic procedures are principally possible but rarely lead to a lasting relief of symptoms. The type of surgical intervention should be selected depending on the morphological changes of the pancreas. Up to 90 % of patients present with an inflammatory mass in the head of the pancreas. In these cases a duodenum-preserving pancreatic head resection (DPPHR) modified according to Beger, Frey or Berne should be preferred. These procedures are comparable in terms of the postoperative course. The Kausch-Whipple procedure is indicated in all cases where malignancy is suspected. According to the current literature, patients with an inflammatory mass in the pancreatic head benefit more from a DPPHR than a Kausch-Whipple procedure. Drainage procedures may be useful for the treatment of pseudocysts or in rare situations with purely ductal obstructions. The decision as to which procedure is appropriate should be taken in an interdisciplinary cooperation between gastroenterologists and surgeons.
慢性胰腺炎可导致顽固性疼痛、胰管梗阻、十二指肠狭窄和血管压迫综合征。手术干预可有效治疗这些症状。内镜手术原则上可行,但很少能持久缓解症状。应根据胰腺的形态学变化选择手术干预的类型。高达90%的患者胰腺头部出现炎性肿块。在这些情况下,应首选根据贝格尔、弗雷或伯恩方法改良的保留十二指肠的胰头切除术(DPPHR)。这些手术在术后过程方面具有可比性。在怀疑有恶性肿瘤的所有病例中均需行考施-惠普尔手术。根据当前文献,胰腺头部有炎性肿块的患者从DPPHR中获益比考施-惠普尔手术更多。引流手术可能有助于治疗假性囊肿或在极少数单纯导管梗阻的情况下使用。关于哪种手术合适的决定应在胃肠病学家和外科医生的多学科合作中做出。