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蜂胶化学成分的最新进展。

Recent advances in the chemical composition of propolis.

作者信息

Huang Shuai, Zhang Cui-Ping, Wang Kai, Li George Q, Hu Fu-Liang

机构信息

College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.

Faculty of Pharmacy, University of Sydney, Sydney, NSW 2006, Australia.

出版信息

Molecules. 2014 Nov 26;19(12):19610-32. doi: 10.3390/molecules191219610.

DOI:10.3390/molecules191219610
PMID:25432012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6271758/
Abstract

Propolis is a honeybee product with broad clinical applications. Current literature describes that propolis is collected from plant resins. From a systematic database search, 241 compounds were identified in propolis for the first time between 2000 and 2012; and they belong to such diverse chemical classes as flavonoids, phenylpropanoids, terpenenes, stilbenes, lignans, coumarins, and their prenylated derivatives, showing a pattern consistent with around 300 previously reported compounds. The chemical characteristics of propolis are linked to the diversity of geographical location, plant sources and bee species.

摘要

蜂胶是一种具有广泛临床应用的蜜蜂产品。目前的文献记载,蜂胶是从植物树脂中采集而来。通过系统的数据库检索,2000年至2012年间首次在蜂胶中鉴定出241种化合物;它们属于黄酮类、苯丙素类、萜类、芪类、木脂素类、香豆素类及其异戊烯基化衍生物等多种不同的化学类别,这一模式与之前报道的约300种化合物一致。蜂胶的化学特性与地理位置、植物来源和蜜蜂种类的多样性有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/7d131cf2a745/molecules-19-19610-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/608519caa691/molecules-19-19610-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/2ffdfd4d811e/molecules-19-19610-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/7d131cf2a745/molecules-19-19610-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/608519caa691/molecules-19-19610-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/2ffdfd4d811e/molecules-19-19610-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9099/6271758/7d131cf2a745/molecules-19-19610-g003.jpg

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Antibacterial activity and phytochemical evidence for the plant origin of Turkish propolis from different regions.不同地区土耳其蜂胶的抗菌活性和植物化学证据。
World J Microbiol Biotechnol. 2007 Dec;23(12):1797-803. doi: 10.1007/s11274-007-9430-7. Epub 2007 May 26.
2
Development of high-performance liquid chromatographic for quality and authenticity control of Chinese propolis.用于中国蜂胶质量与真伪控制的高效液相色谱法的开发
J Food Sci. 2014 Jul;79(7):C1315-22. doi: 10.1111/1750-3841.12510. Epub 2014 Jun 3.
3
Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae).
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Med Oncol. 2025 Aug 26;42(10):449. doi: 10.1007/s12032-025-03023-6.
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Suggestions for resin research under the COST Action EU-PoTaRCh.在欧洲科学与技术合作组织(COST)“欧盟植物资源化学研究与保护行动”(EU-PoTaRCh)下关于树脂研究的建议。
Open Res Eur. 2025 Aug 4;4:272. doi: 10.12688/openreseurope.18988.2. eCollection 2024.
5
Potential Therapeutic Actions of Flavonoids Present in Propolis That Modulate Vascular Endothelial Growth Factor Signaling to Regulate Angiogenesis.蜂胶中存在的类黄酮调节血管内皮生长因子信号传导以调控血管生成的潜在治疗作用。
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Food-Drug Interactions: Effect of Propolis on the Pharmacokinetics of Enrofloxacin and Its Active Metabolite Ciprofloxacin in Rabbits.食物-药物相互作用:蜂胶对家兔恩诺沙星及其活性代谢物环丙沙星药代动力学的影响。
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Cytotoxic Activity of Six Samples of Brazilian Propolis on Sea Urchin (Lytechinus variegatus) Eggs.巴西蜂胶六种样品对海胆(Lytechinus variegatus)卵的细胞毒性活性。
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