Yamaguchi K, Maeda S, Kitamura K
Department of Surgery, Shin Kokura Hospital, Kitakyushu, Japan.
Am J Gastroenterol. 1989 Jun;84(6):656-9.
In a 64-yr-old Japanese man, granular cell tumor of the stomach plus two early gastric carcinomas were detected. The granular cell tumor was a 1.5 x 1.5-cm submucosal nodule located in the posterior wall of the fundus. The mucosa adjacent to the granular cell tumor showed two well-differentiated adenocarcinomas restricted to the mucosa, but there was no continuity among these three conditions. This seems to be the first report of this type of association. Immunohistochemical study revealed S-100 protein in the component cells of the granular cell tumor, thereby supporting the proposal that this granular cell is derived from Schwann cells.
在一名64岁的日本男性中，发现了胃颗粒细胞瘤合并两处早期胃癌。颗粒细胞瘤是一个位于胃底后壁的1.5×1.5厘米的黏膜下结节。与颗粒细胞瘤相邻的黏膜显示出两处局限于黏膜层的高分化腺癌，但这三种病变之间没有连续性。这似乎是此类关联的首例报告。免疫组织化学研究显示颗粒细胞瘤的组成细胞中有S-100蛋白，从而支持了这种颗粒细胞来源于施万细胞的观点。
