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身体问题:重新思考针对儿童的非有益性临床研究的伦理可接受性。

Body matters: rethinking the ethical acceptability of non-beneficial clinical research with children.

作者信息

De Clercq Eva, Badarau Domnita Oana, Ruhe Katharina M, Wangmo Tenzin

机构信息

Institute for Biomedical Ethics, University of Basel, Bernoullistr 28, 4056, Basel, Switzerland,

出版信息

Med Health Care Philos. 2015 Aug;18(3):421-31. doi: 10.1007/s11019-014-9616-3.

Abstract

The involvement of children in non-beneficial clinical research is extremely important for improving pediatric care, but its ethical acceptability is still disputed. Therefore, various pro-research justifications have been proposed throughout the years. The present essay aims at contributing to the on-going discussion surrounding children's participation in non-beneficial clinical research. Building on Wendler's 'contribution to a valuable project' justification, but going beyond a risk/benefit analysis, it articulates a pro-research argument which appeals to a phenomenological view on the body and vulnerability. It is claimed that children's bodies are not mere physical objects, but body-subjects due to which children, as persons, can contribute to research that may hold no direct clinical benefit to them even before they can give informed consent.

摘要

让儿童参与非有益性临床研究对于改善儿科护理极为重要,但其伦理可接受性仍存在争议。因此,多年来人们提出了各种支持研究的理由。本文旨在为围绕儿童参与非有益性临床研究的持续讨论做出贡献。基于温德勒的“对有价值项目的贡献”理由,但超越风险/收益分析,本文阐述了一种支持研究的观点,该观点诉诸对身体和脆弱性的现象学看法。有人认为,儿童的身体不仅仅是物理对象,而是身体主体,正因为如此,儿童作为人,即使在能够给出知情同意之前,也可以为对他们可能没有直接临床益处的研究做出贡献。

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