外周动脉疾病中的药理学：介入放射科医生需要了解的内容。
Pharmacology in peripheral arterial disease: what the interventional radiologist needs to know.
作者信息
Atturu Gnaneswar, Homer-Vanniasinkam Shervanthi, Russell David A
机构信息
Leeds Vascular Institute, Leeds General Infirmary, Leeds, United Kingdom.
出版信息
Semin Intervent Radiol. 2014 Dec;31(4):330-7. doi: 10.1055/s-0034-1393969.
Abstract
Peripheral arterial disease (PAD) is a progressive disease with significant morbidity and mortality. Risk factor control, using diet and lifestyle modification, exercise, and pharmacological methods, improves symptoms and reduces associated cardiovascular events in these patients. Antiplatelet agents and anticoagulants may be used to reduce the incidence of acute events related to thrombosis. The armamentarium available for symptom relief and disease modification is discussed. Novel treatments such as therapeutic angiogenesis are in their evolutionary phase with promising preclinical data.
摘要
外周动脉疾病（PAD）是一种具有显著发病率和死亡率的进展性疾病。通过饮食和生活方式改变、运动及药物治疗等方法控制危险因素，可改善这些患者的症状并减少相关心血管事件。抗血小板药物和抗凝剂可用于降低与血栓形成相关的急性事件的发生率。本文讨论了可用于缓解症状和改善疾病的治疗手段。诸如治疗性血管生成等新型治疗方法正处于发展阶段，临床前数据很有前景。
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