Wang Ying, Yang Li, Qian Zi-Hua, Zhu Xiu-Liang, Yu Ri-Sheng
Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.
Oncol Lett. 2015 Jan;9(1):219-222. doi: 10.3892/ol.2014.2691. Epub 2014 Nov 7.
Solitary extramedullary plasmacytoma (EMP) of the spleen is a rare condition. The present study describes the case of a 23-year-old female with an extremely rare solitary EMP of the spleen. Upon examination, the tumor demonstrated unusual and notable multiple-phase spiral computed tomography (CT) findings. The lesion was a solitary, well-defined mass, with areas of variable splenic necrosis and cystic degeneration. Contrast-enhanced CT revealed progressive enhancement of the lesion in the cystic wall, internal septa and solid portion, a finding that has not previously been described. The patient underwent a splenectomy and recovered without complications. No evidence of tumor recurrence has occurred during the past two years of follow-up. To the best of our knowledge, this is the first study to examine the CT findings of a solitary EMP of the spleen. The study aimed to investigate the imaging features of solitary EMP, in particular the multiple-phase spiral CT findings, and raise awareness of the disease to reduce misdiagnoses.
脾脏孤立性髓外浆细胞瘤(EMP)是一种罕见疾病。本研究描述了一名23岁女性患有极其罕见的脾脏孤立性EMP的病例。经检查,该肿瘤表现出不寻常且显著的多期螺旋计算机断层扫描(CT)结果。病变为一个孤立的、边界清晰的肿块,伴有脾实质坏死和囊性变区域。增强CT显示病变在囊壁、内部间隔和实性部分呈渐进性强化,这一发现此前未见报道。患者接受了脾切除术,术后恢复良好,无并发症。在过去两年的随访中未发现肿瘤复发迹象。据我们所知,这是第一项研究脾脏孤立性EMP的CT表现的研究。该研究旨在探讨孤立性EMP的影像学特征,尤其是多期螺旋CT表现,并提高对该疾病的认识以减少误诊。