Colović M D, Janković G M, Colović R B, Martinović-Cemerikić V M
Institute of Hematology, Clinical Center of Serbia, Belgrade, Yugoslavia.
Med Oncol. 1998 Dec;15(4):286-8. doi: 10.1007/BF02787215.
A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal survey showed no signs of myeloma. Biopsy of the liver and regional lymph nodes was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treated with chemotherapy according to protocol VBCMP (M2).
报告一例脾脏原发性非分泌性浆细胞瘤。剖腹探查及脾切除术切除了一个重920克的脾脏，尺寸为16×14×6厘米。整个脾脏的切面显示肿瘤占据了大部分脾组织。骨髓穿刺及活检、骨骼检查均未发现骨髓瘤迹象。肝脏及区域淋巴结活检正常。脾脏肿瘤的免疫细胞化学显示泛B和浆细胞标志物呈阳性。脾切除术后，患者按照VBCMP（M2）方案接受化疗。
