Puolijoki H, Nieminen M, Moilanen E, Siitonen L, Lahdensuo A, Reinikainen P, Vapaatalo H
Tampere University Central Hospital, Finland.
Eur Respir J. 1989 Mar;2(3):289-91.
We report a 68 yr old woman with hypertension who developed a dry cough on enalapril but not on captopril therapy. Pulmonary function tests, methacholine inhalation challenges, total blood eosinophil counts, and changes in plasma concentrations of prostaglandin E2 and thromboxane B2 did not explain the difference in the adverse reaction between these two angiotensin converting enzyme inhibitors.
我们报告了一位68岁的高血压女性患者,她在服用依那普利时出现干咳,但服用卡托普利时未出现。肺功能测试、乙酰甲胆碱吸入激发试验、全血嗜酸性粒细胞计数以及前列腺素E2和血栓素B2血浆浓度的变化均无法解释这两种血管紧张素转换酶抑制剂在不良反应上的差异。