Fan C C, Shimomura Y, Inoue Y, Watanabe H, Iwasaki N, Matsuda M, Manabe R, Ihara M, Harada S, Yanagi K
Department of Ophthalmology, Osaka University Medical School, Japan.
Jpn J Ophthalmol. 1989;33(1):120-4.
The patient, a 56-year-old man, presented with dendritic keratitis in the right eye and geographic keratitis in the left, with decreased corneal sensation in both eyes. The virus isolated from both eyes was identified as herpes simplex virus (HSV-1) by the indirect immunofluorescent method using anti-HSV-1 monoclonal antibody. Antibody tests of paired sera suggested that the epithelial lesions were not primary but recurrent. No significant difference was observed in DNA cleavage patterns between the virus isolates obtained bilaterally.
该患者为一名56岁男性，右眼患有树枝状角膜炎，左眼患有地图状角膜炎，双眼角膜感觉减退。使用抗单纯疱疹病毒1型（HSV-1）单克隆抗体的间接免疫荧光法将从双眼分离出的病毒鉴定为单纯疱疹病毒1型（HSV-1）。双份血清的抗体检测表明，上皮病变并非原发性而是复发性的。双侧获得的病毒分离株之间的DNA切割模式未观察到显著差异。
