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益生元的最新进展:选择性影响有益微生物并促进肠道健康。

Recent developments in prebiotics to selectively impact beneficial microbes and promote intestinal health.

作者信息

Rastall Robert A, Gibson Glenn R

机构信息

Department of Food and Nutritional Sciences, The University of Reading, Whiteknights, Reading RG6 6AP, UK.

Department of Food and Nutritional Sciences, The University of Reading, Whiteknights, Reading RG6 6AP, UK.

出版信息

Curr Opin Biotechnol. 2015 Apr;32:42-46. doi: 10.1016/j.copbio.2014.11.002. Epub 2014 Nov 21.

Abstract

Prebiotics are non-digestible food ingredients that have a specific stimulatory effect upon selected populations of gut bacteria. The usual target microorganisms for prebiotic approaches are bifidobacteria. Numerous human feeding studies have shown the prebiotic influences that galactans and fructans can exert. Other candidate prebiotics are under investigation. The field is now moving towards identifying the health aspect associated with their use. Many avenues of gut related health are being researched, including reduction of diarrhoea, immune stimulation, and improved mineral bioavailability. Most current emphasis appears to be towards various parameters associated with metabolic syndrome. These include markers of insulin resistance, appetite, satiety, blood lipids and inflammatory status.

摘要

益生元是不可消化的食物成分,对特定的肠道细菌群体具有特定的刺激作用。益生元方法通常针对的目标微生物是双歧杆菌。大量人体喂养研究表明了半乳聚糖和果聚糖所能发挥的益生元影响。其他候选益生元正在研究中。该领域目前正朝着确定与它们的使用相关的健康方面发展。许多与肠道相关的健康途径正在被研究,包括腹泻的减少、免疫刺激以及矿物质生物利用度的提高。当前大多数重点似乎放在与代谢综合征相关的各种参数上。这些参数包括胰岛素抵抗、食欲、饱腹感、血脂和炎症状态的标志物。

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