The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Am J Ophthalmol. 2015 Feb;159(2):241-7.e2. doi: 10.1016/j.ajo.2014.10.025. Epub 2014 Nov 1.
To investigate the relationship among Lens Opacities Classification System III (LOCS III) grading score, Visual Function Index-14 (VF-14) score, average lens density by the Pentacam Nucleus Staging system, and the objective scatter index measured by the Optical Quality Analysis System in age-related cataract patients.
Prospective, single-center, cross-sectional study.
Thirty-six subjects (60 eyes) with age-related cataract were recruited. Subjects with any corneal anomaly potentially affecting intraocular scatter were excluded. The best-corrected visual acuity (BCVA), LOCS III nuclear opalescence score and cortical cataract score, VF-14 score, average lens density, and objective scatter index were obtained. Correlations among these parameters were analyzed.
The LOCS III nuclear opalescence score was correlated with the BCVA (r = 0.438; P = .001), objective scatter index (r = 0.543; P < .001), and average lens density (r = 0.621; P < .001). The objective scatter index was also correlated with the BCVA (r = 0.779; P < .001) and the average lens density (r = 0.320; P = .013). The VF-14 score had the strongest correlation with the objective scatter index (r = -0.712; P < .001). The difference between groups with objective scatter index<3.0 and ≥3.0 was significant with regard to BCVA, average lens density, LOCS III nuclear opalescence score, and VF-14 score.
LOCS III grading remains an economical and effective method to assess lens opacities, especially in the formation of early cortex cataracts. The objective scatter index can be a useful parameter to objectively analyze the correlation between ocular examination findings and patient concerns. Furthermore, the objective scatter index scores ≥3.0 can be a possible objective cut-off for preoperative decision making.
研究 Lens Opacities Classification System III (LOCS III) 分级评分、Visual Function Index-14 (VF-14) 评分、Pentacam 核分期系统平均晶状体密度与 Optical Quality Analysis System 测量的客观散射指数在年龄相关性白内障患者中的关系。
前瞻性、单中心、横断面研究。
招募 36 名(60 只眼)年龄相关性白内障患者。排除任何可能影响眼内散射的角膜异常患者。获得最佳矫正视力(BCVA)、LOCS III 核混浊评分和皮质白内障评分、VF-14 评分、平均晶状体密度和客观散射指数。分析这些参数之间的相关性。
LOCS III 核混浊评分与 BCVA(r = 0.438;P =.001)、客观散射指数(r = 0.543;P <.001)和平均晶状体密度(r = 0.621;P <.001)相关。客观散射指数也与 BCVA(r = 0.779;P <.001)和平均晶状体密度(r = 0.320;P =.013)相关。VF-14 评分与客观散射指数的相关性最强(r = -0.712;P <.001)。客观散射指数<3.0 和≥3.0 两组间的 BCVA、平均晶状体密度、LOCS III 核混浊评分和 VF-14 评分差异有统计学意义。
LOCS III 分级仍然是评估晶状体混浊的一种经济有效的方法,特别是在早期皮质白内障的形成中。客观散射指数可以作为客观分析眼部检查结果与患者关注点之间相关性的有用参数。此外,客观散射指数评分≥3.0 可能是术前决策的一个潜在客观截止值。