Thomas Jessica M, Huber Elizabeth, Stecker G Christopher, Boynton Geoffrey M, Saenz Melissa, Fine Ione
Department of Psychology, University of Washington, Seattle WA 98195-1525, USA.
Department of Psychology, University of Washington, Seattle WA 98195-1525, USA.
Neuroimage. 2015 Jan 15;105:428-39. doi: 10.1016/j.neuroimage.2014.10.060. Epub 2014 Nov 7.
Here we describe a method for measuring tonotopic maps and estimating bandwidth for voxels in human primary auditory cortex (PAC) using a modification of the population Receptive Field (pRF) model, developed for retinotopic mapping in visual cortex by Dumoulin and Wandell (2008). The pRF method reliably estimates tonotopic maps in the presence of acoustic scanner noise, and has two advantages over phase-encoding techniques. First, the stimulus design is flexible and need not be a frequency progression, thereby reducing biases due to habituation, expectation, and estimation artifacts, as well as reducing the effects of spatio-temporal BOLD nonlinearities. Second, the pRF method can provide estimates of bandwidth as a function of frequency. We find that bandwidth estimates are narrower for voxels within the PAC than in surrounding auditory responsive regions (non-PAC).
在此，我们描述了一种测量人类初级听觉皮层（PAC）中体素的音调拓扑图并估计其带宽的方法，该方法是对群体感受野（pRF）模型进行修改后得到的，此模型由杜穆林和万德尔（2008年）为视觉皮层的视网膜拓扑映射而开发。在存在声学扫描仪噪声的情况下，pRF方法能够可靠地估计音调拓扑图，并且与相位编码技术相比具有两个优点。第一，刺激设计灵活，不必是频率递进，从而减少了由于习惯化、期望和估计伪影导致的偏差，同时也减少了时空BOLD非线性的影响。第二，pRF方法可以提供作为频率函数的带宽估计。我们发现，PAC内体素的带宽估计比周围听觉响应区域（非PAC）中的更窄。
