González Hector M, Tarraf Wassim, Gouskova Natalia, Gallo Linda C, Penedo Frank J, Davis Sonia M, Lipton Richard B, Argüelles William, Choca James P, Catellier Diane J, Mosley Thomas H
Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, USA
Institute of Gerontology, Wayne State University, Detroit, MI, USA.
Arch Clin Neuropsychol. 2015 Feb;30(1):68-77. doi: 10.1093/arclin/acu066. Epub 2014 Dec 1.
We sought to examine and describe neurocognitive function among middle-aged and older Hispanic/Latino Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants. We analyzed baseline cross-sectional data from the middle-aged and older (ages 45-74 years old) participants (n = 9,063) to calculate neurocognitive function scores and their correlates. Older age and higher depressive symptoms scores were associated with lower average neurocognitive performance, whereas greater educational attainment and household income were associated with higher neurocognitive performance. Hispanic/Latino heritage groups significantly varied in neurocognitive performances. Some neurocognitive differences between Hispanics/Latinos were maintained after controlling for language preference, education, household income, and depressive symptoms. We found notable differences in neurocognitive scores between Hispanic/Latino heritage groups that were not fully explained by the cultural and socioeconomic correlates examined in this study. Further investigations into plausible biological and environmental factors contributing to the Hispanic/Latino heritage group differences in neurocognitive found in the HCHS/SOL are warranted.
我们试图对西班牙裔/拉丁裔社区健康研究/拉丁裔研究（HCHS/SOL）中的中老年参与者的神经认知功能进行检测和描述。我们分析了中老年（45 - 74岁）参与者（n = 9,063）的基线横断面数据，以计算神经认知功能得分及其相关因素。年龄较大和抑郁症状得分较高与平均神经认知表现较低相关，而受教育程度较高和家庭收入较高与神经认知表现较高相关。西班牙裔/拉丁裔血统群体在神经认知表现上存在显著差异。在控制了语言偏好、教育程度、家庭收入和抑郁症状后，西班牙裔/拉丁裔之间的一些神经认知差异仍然存在。我们发现西班牙裔/拉丁裔血统群体之间的神经认知得分存在显著差异，而本研究中所考察的文化和社会经济相关因素并不能完全解释这些差异。有必要对HCHS/SOL中发现的导致西班牙裔/拉丁裔血统群体神经认知差异的可能的生物学和环境因素进行进一步研究。
