Department of Gastroenterology and Hepatology, Centro Hospitalar de Gaia/Espinho, Gaia, Portugal.
United European Gastroenterol J. 2014 Dec;2(6):490-6. doi: 10.1177/2050640614554850.
We aimed to evaluate the impact of emergency single-balloon enteroscopy (SBE) on the diagnosis and treatment for active overt obscure gastrointestinal bleeding (OGIB).
SBE procedures for OGIB were retrospectively reviewed and sub-divided according to the bleeding types: active-overt and inactive-overt bleeding. The patient's history, laboratory results, endoscopic findings and therapeutic interventions were registered. Emergency SBE was defined as an endoscopy that was performed for active-overt OGIB, within 24 hours of clinical presentation.
Between January 2010 and February 2013, 53 SBEs were performed in 43 patients with overt OGIB. Seventeen emergency SBEs were performed in 15 patients with active overt-OGIB procedures (group A), which diagnosed the bleeding source in 14: angiodysplasia (n = 5), ulcers/erosions (n = 3), bleeding tumors (gastrointestinal stromal tumor (GIST), n = 3; neuroendocrine tumor, n = 1), and erosioned polyps (n = 2). Endoscopic treatment was performed in nine patients, with one or multiple hemostatic therapies: argon plasma coagulation (n = 5), epinephrine submucosal injection (n = 5), hemostatic clips (n = 3), and polypectomy (n = 2). Twenty-eight patients with inactive bleeding (group B) were submitted to 36 elective SBEs, which successfully diagnosed 18 cases. The diagnostic yield in group A (93.3%) was significantly higher than in group B (64.3%)-Fisher's exact test, p = 0.038.
This study revealed an important role of emergency SBE in the diagnosis of bleeding etiology in active overt OGIB.
评估急诊单气囊小肠镜(SBE)对显性非静脉曲张性胃肠道出血(OGIB)的诊断和治疗的影响。
回顾性分析 SBE 治疗 OGIB 的资料,根据出血类型进行亚组划分:显性和非显性出血。记录患者的病史、实验室结果、内镜表现和治疗干预措施。将在发病后 24 小时内进行的用于治疗显性 OGIB 的内镜检查定义为急诊 SBE。
2010 年 1 月至 2013 年 2 月期间,43 例显性 OGIB 患者接受了 53 例 SBE 检查。15 例显性 OGIB 伴活动性出血患者(A 组)进行了 17 例急诊 SBE,其中 14 例确定了出血源:血管发育不良(n=5)、溃疡/糜烂(n=3)、出血性肿瘤(胃肠道间质瘤(GIST),n=3;神经内分泌肿瘤,n=1)、糜烂性息肉(n=2)。9 例患者接受了内镜治疗,采用了一种或多种止血治疗方法:氩等离子凝固术(n=5)、肾上腺素黏膜下注射(n=5)、止血夹(n=3)、息肉切除术(n=2)。28 例非活动性出血患者(B 组)接受了 36 例择期 SBE,其中 18 例成功诊断。A 组(93.3%)的诊断率明显高于 B 组(64.3%)(Fisher 确切概率检验,p=0.038)。
本研究表明,急诊 SBE 在诊断显性 OGIB 患者出血病因方面发挥着重要作用。