Kazemi Asif, Amini Afshin
Dept. of Anesthesiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Middle East J Anaesthesiol. 2007 Feb;19(1):197-204.
Tracheal intubation for general anesthesia often leads to traumatization of the airway mucosa resulting in postoperative sore throat, hoarseness and cough. This study was undertaken to determine the effects of betamethasone gel in reducing these complications.
One hundred patients (ASA I-II) to undergo endotracheal intubation, were randomly divided equally into two groups; 50 Case (Group A). 50 Control (Group B). The tracheal tubes for Case Group A were lubricated with 0.05% betamethasone gel and for the Control Group B with KY gel. Patients were interviewed at end of procedures and 1 and 24 hour after extubation.
The incidence and severity of sore throat, hoarseness and cough, 1 and 24 hours postoperatively was reduced significantly in Case Group A.
Betamethasone gel, when was used for lubrication of endotracheal tubes pre-operatively, was shown to be effective in decreasing postoperative sore throat, hoarseness, and cough.
全身麻醉时气管插管常导致气道黏膜损伤，引起术后咽痛、声音嘶哑和咳嗽。本研究旨在确定倍他米松凝胶在减少这些并发症方面的效果。
100例拟行气管插管的患者（ASA I-II级）被随机均分为两组；50例为病例组（A组），50例为对照组（B组）。A组病例的气管导管用0.05%倍他米松凝胶润滑，B组对照组用KY凝胶润滑。在手术结束时以及拔管后1小时和24小时对患者进行访谈。
A组病例术后1小时和24小时咽痛、声音嘶哑和咳嗽的发生率及严重程度均显著降低。
术前将倍他米松凝胶用于气管导管润滑，可有效降低术后咽痛、声音嘶哑和咳嗽的发生率。
