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母体免疫可使母亲、胎儿和婴儿受益。

Maternal immunization to benefit the mother, fetus, and infant.

作者信息

Swamy Geeta K, Garcia-Putnam Rebecca

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Duke University, Durham, NC 27705, USA.

Department of Obstetrics & Gynecology, Duke University, Durham, NC 27705, USA.

出版信息

Obstet Gynecol Clin North Am. 2014 Dec;41(4):521-34. doi: 10.1016/j.ogc.2014.08.001. Epub 2014 Nov 20.

Abstract

Pregnant women are at risk for the same infectious diseases as nonpregnant individuals and often have increased morbidity and mortality associated with infection. Thus, immunizing women during pregnancy with recommended vaccines provides direct maternal benefit. Furthermore, maternal immunization has the potential for both fetal and infant benefit by preventing adverse pregnancy outcomes and infection during early life through passive immunity. This article reviews current knowledge on the importance and benefits of maternal immunization, which are 3-fold: protecting the mother from antepartum infection; reducing poor pregnancy and fetal outcomes; and providing immunity for infants during the first few months of life.

摘要

孕妇与非孕妇面临相同的传染病风险,且感染相关的发病率和死亡率往往更高。因此,在孕期为女性接种推荐疫苗可直接使母亲受益。此外,母体免疫有可能通过被动免疫预防不良妊娠结局和早期感染,从而使胎儿和婴儿受益。本文综述了关于母体免疫重要性和益处的现有知识,其益处有三方面:保护母亲免受产前感染;减少不良妊娠和胎儿结局;为婴儿在出生后的头几个月提供免疫力。

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