Perrett Kirsten P, Nolan Terry M
Vaccine and Immunisation Research Group, Murdoch Childrens Research Institute and Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.
Melbourne Children's Trial Centre, Murdoch Childrens Research Institute, Melbourne, VIC, Australia.
Paediatr Drugs. 2017 Aug;19(4):313-324. doi: 10.1007/s40272-017-0231-7.
Maternal immunization has undergone a paradigm shift in recent years, as women and healthcare providers accept and recognize the benefits of this strategy not only for the pregnant woman but also for the developing fetus and young infant. This article reviews the evidence for active immunization during pregnancy, with an emphasis on perinatal and infant outcomes. Current recommendations for immunization during pregnancy are presented, with particular focus on the routinely recommended vaccines during pregnancy: influenza and Tdap (tetanus, diphtheria, and pertussis). We discuss future research directions, maternal vaccines in development, and considerations for optimizing and advancing this underutilized strategy.
近年来，孕产妇免疫接种发生了范式转变，因为女性和医疗服务提供者不仅认识到这一策略对孕妇有益，而且对发育中的胎儿和幼儿也有益。本文回顾了孕期主动免疫的证据，重点关注围产期和婴儿结局。文中列出了目前关于孕期免疫接种的建议，特别关注孕期常规推荐的疫苗：流感疫苗和百白破疫苗（破伤风、白喉和百日咳疫苗）。我们讨论了未来的研究方向、正在研发的孕产妇疫苗，以及优化和推进这一未得到充分利用的策略的注意事项。
