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[玄武岩纤维与温石棉的比较致癌特性]

[Comparative carcinogenic properties of basalt fiber and chrysotile-asbestos].

作者信息

Nikitina O V, Kogan F M, Vanchugova N N, Frash V N

出版信息

Gig Tr Prof Zabol. 1989(4):7-11.

PMID:2545547
Abstract

In order to eliminate asbestos adverse effect on workers' health it was necessary to use mineral rayon, primarily basalt fibre, instead of asbestos. During a chronic experiment on animals the oncogenicity of 2 kinds of basalt fibre was studied compared to chrysotile asbestos. The dust dose of 25 mg was twice administered by intraperitonial route. All types of dust induced the onset of intraperitonial mesotheliomas but neoplasm rates were significantly lower in the groups exposed to basalt fibre. There was no credible data on the differences between the groups exposed to various types of basalt fibre. Since the latter produced some oncogenic effect, it was necessary to develop a complex of antidust measures, fully corresponding to the measures adopted for carcinogenic dusts.

摘要

为消除石棉对工人健康的不利影响,有必要使用矿物纤维,主要是玄武岩纤维,来替代石棉。在一项针对动物的慢性实验中,研究了两种玄武岩纤维与温石棉相比的致癌性。通过腹腔途径两次给予25毫克的粉尘剂量。所有类型的粉尘都引发了腹腔间皮瘤,但接触玄武岩纤维的组中的肿瘤发生率显著较低。关于接触不同类型玄武岩纤维的组之间的差异,没有可靠的数据。由于后者产生了一些致癌作用,有必要制定一套完整的防尘措施,使其完全符合针对致癌粉尘所采取的措施。

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