Fuldeore Mahesh, Yang Hongbo, Du Ella Xiaoyan, Soliman Ahmed M, Wu Eric Q, Winkel Craig
AbbVie, Inc., North Chicago, Illinois.
Analysis Group, Inc., Boston, Massachusetts.
Fertil Steril. 2015 Jan;103(1):163-71. doi: 10.1016/j.fertnstert.2014.10.011. Epub 2014 Nov 15.
To assess healthcare resource utilization and costs during the 5 years before and 5 years after diagnosis among women with endometriosis, in comparison with women without endometriosis.
Longitudinal, retrospective, case-control study.
None.
PATIENT(S): A total of 37,570 matched pairs of women with and without (controls) endometriosis were identified from the Truven Health MarketScan claims database (2000-2010).
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Annual healthcare resource utilization and costs (in 2010 US dollars) were evaluated for the 5 years before and 5 years after diagnosis.
RESULT(S): Mean patient age at index (first diagnosis) date was 36.4 years for endometriosis patients and controls. Endometriosis patients had a higher utilization of outpatient and emergency room services during each pre- and postindex year, and a higher utilization of inpatient services during the last preindex year and all 5 postindex years. Total costs were highest in the first postindex year for endometriosis patients, reaching $13,199, compared with $3,747 for controls. Annual costs were significantly higher for patients than controls during each pre- and postindex year; overall, the cost difference was $26,305 over 10 years: $7,028 in the 5 years before diagnosis and $19,277 in the 5 years after diagnosis.
CONCLUSION(S): Endometriosis poses a significantly high economic burden, both before and after diagnosis. The highest resource utilization and costs experienced by endometriosis patients occur in the first year after diagnosis.
评估子宫内膜异位症女性患者诊断前5年及诊断后5年的医疗资源利用情况和费用,并与无子宫内膜异位症的女性进行比较。
纵向、回顾性病例对照研究。
无。
从Truven Health MarketScan理赔数据库(2000 - 2010年)中识别出总共37570对匹配的患有和未患有(对照)子宫内膜异位症的女性。
无。
评估诊断前5年及诊断后5年的年度医疗资源利用情况和费用(以2010年美元计)。
子宫内膜异位症患者和对照在索引(首次诊断)日期的平均患者年龄为36.4岁。子宫内膜异位症患者在索引前后各年的门诊和急诊服务利用率较高,在索引前最后一年和索引后所有5年的住院服务利用率较高。子宫内膜异位症患者在索引后第一年的总费用最高,达到13199美元,而对照为3747美元。在索引前后各年,患者的年度费用均显著高于对照;总体而言,10年的费用差异为26305美元:诊断前5年为7028美元,诊断后5年为19277美元。
子宫内膜异位症在诊断前后均带来显著的高经济负担。子宫内膜异位症患者最高的资源利用和费用发生在诊断后的第一年。