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前额叶皮层-内侧颞叶振荡相互作用的丘脑通路。

Thalamic pathways underlying prefrontal cortex-medial temporal lobe oscillatory interactions.

机构信息

Department of Psychology and Neuroscience, University of Colorado Boulder, 345 UCB, Boulder, CO, USA.

Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, 6500HB, Nijmegen, The Netherlands.

出版信息

Trends Neurosci. 2015 Jan;38(1):3-12. doi: 10.1016/j.tins.2014.09.007. Epub 2014 Oct 22.

DOI:10.1016/j.tins.2014.09.007
PMID:25455705
Abstract

As focus shifts to large-scale network interactions involved in memory, it is becoming increasingly clear that oscillatory dynamics are critically involved. A number of studies have shown a negative correlation between memory retrieval in alpha and beta power, and a positive correlation between retrieval and theta power. In this opinion article, we suggest three thalamic sub-regions responsible for the coordination of oscillatory activity and the facilitation of memory processes. Specifically, the medial dorsal nucleus is related to changes in beta synchrony, the pulvinar is responsible for alpha synchrony, and the anterior thalamus is related to theta synchrony. These pathways may be modulated via frontal control, and changes in oscillations could be used to track the engagement of underlying memory systems.

摘要

随着研究重点转移到涉及记忆的大规模网络相互作用上,越来越明显的是,震荡动态是至关重要的。许多研究表明,在α和β波功率的记忆检索之间存在负相关,而在θ波功率的检索之间存在正相关。在这篇观点文章中,我们提出了三个丘脑亚区,它们负责协调震荡活动并促进记忆过程。具体来说,内侧背核与β同步变化有关,丘闩负责α同步,前丘脑与θ同步有关。这些通路可以通过额叶控制来调节,并且震荡的变化可以用来跟踪潜在记忆系统的参与。

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