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通过免疫印迹法在一名吉兰-巴雷综合征患者脑脊液中检测到的单纯疱疹病毒特异性抗体。

Herpes simplex virus specific antibody determined by immunoblotting in cerebrospinal fluid of a patient with the Guillain-Barré syndrome.

作者信息

Bernsen H J, Van Loon A M, Poels R F, Verhagen W I, Frenken C W

机构信息

Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.

出版信息

J Neurol Neurosurg Psychiatry. 1989 Jun;52(6):788-91. doi: 10.1136/jnnp.52.6.788.

DOI:10.1136/jnnp.52.6.788
PMID:2545828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1032036/
Abstract

The Guillain-Barré syndrome is often preceded by a herpes virus infection. Herpes simplex virus, however, has rarely been observed as the causative agent. A patient is described with a herpes simplex virus infection followed by a Guillain-Barré syndrome. Immunoblotting was used to detect herpes simplex virus-specific antibodies in serum and cerebrospinal fluid.

摘要

吉兰-巴雷综合征通常在疱疹病毒感染后出现。然而，单纯疱疹病毒作为致病原很少被观察到。本文描述了一名患者，先出现单纯疱疹病毒感染，随后发生吉兰-巴雷综合征。采用免疫印迹法检测血清和脑脊液中的单纯疱疹病毒特异性抗体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1fc/1032036/35daaa602b6b/jnnpsyc00528-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1fc/1032036/35daaa602b6b/jnnpsyc00528-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1fc/1032036/35daaa602b6b/jnnpsyc00528-0097-a.jpg

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本文引用的文献

1
ROLE OF INFECTION IN THE GUILLAIN-BARR'E SYNDROME.感染在吉兰-巴雷综合征中的作用
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Polyneuropathy after herpes simplex type 2 meningitis.2型单纯疱疹性脑膜炎后的多发性神经病
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A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots.一种在蛋白质免疫印迹法中检测碱性磷酸酶偶联抗抗体的快速、灵敏方法。
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Relative titers of antibodies to individual polypeptide antigens of herpes simplex virus type 1 in human sera.人血清中针对单纯疱疹病毒1型各多肽抗原的抗体相对滴度。
J Infect Dis. 1983 Sep;148(3):436-44. doi: 10.1093/infdis/148.3.436.
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Immunology of Guillain-Barré syndrome.吉兰-巴雷综合征的免疫学
Springer Semin Immunopathol. 1985;8(3):165-76. doi: 10.1007/BF00197294.
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Risk factors for Guillain-Barré syndrome.吉兰-巴雷综合征的危险因素。
Neurology. 1987 Apr;37(4):685-8. doi: 10.1212/wnl.37.4.685.
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Class II antigen expression and inflammatory cells in the Guillain-Barré syndrome.
Ann Neurol. 1987 Apr;21(4):337-41. doi: 10.1002/ana.410210404.
10
Effects of the modification of transfer buffer composition and the renaturation of proteins in gels on the recognition of proteins on Western blots by monoclonal antibodies.转移缓冲液成分的改变及凝胶中蛋白质复性对单克隆抗体在蛋白质印迹法中识别蛋白质的影响。
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