Cameriere Roberto, Santoro Valeria, Roca Roberta, Lozito Piercarlo, Introna Francesco, Cingolani Mariano, Galić Ivan, Ferrante Luigi
AgEstimation Project, Institute of Legal Medicine, Macerata, Italy.
Section of Legal Medicine, University of Bari, Bari, Italy.
Forensic Sci Int. 2014 Dec;245:205.e1-5. doi: 10.1016/j.forsciint.2014.10.013. Epub 2014 Oct 13.
The third molar tooth is one of the few anatomical structures in development available for estimating the age of individuals in the late adolescence. This study tests the accuracy of Cameriere's cut-off value of the third molar index (I3M) in assessing legal adult age of 18 years in an Albanian sample. For this purpose, a sample of orthopantomograms (OPTs) of 286 living subjects (152 female and 134 male) aged between 15 and 22 years was analyzed. Intra-rater and inter-raters agreement of I3M were 0.998 and 0.998, respectively and Cohen Kappa for intra-rater and inter-rater agreement in decision on adult or minor was 1.0 and 1.0, respectively. Age distribution gradually decreases as I3M increases in both males and females. The mean age of females is higher than that of males when I3M is between 0.04 and 0.08. Sensitivity test for males was 94.1%, with a 95% confidence interval (95% CI) 85.6-98.4%, and specificity was 90.9% (95%CI 81.3-96.6%). The proportion of correctly classified individuals was 92.5%, with a 95%CI of (86.7%, 96.4%). For females, the sensitivity test was 75.4%, with a 95%CI of (63.1%, 85.2%) and specificity was 96.6%, with a 95%CI of (90.3%, 99.3%). The proportion of correctly classified individuals was 87.5%, with a 95%CI of (81.2%, 92.3%). The results indicate that Cameriere's cut-off value of the third molar index (I3M=0.08) is useful in discriminating between Albanian adults and juveniles, and encourage us to test its suitability for determining the adult age in individuals from other populations.
第三磨牙是发育过程中少数可用于估计青少年晚期个体年龄的解剖结构之一。本研究在一个阿尔巴尼亚样本中测试了卡梅里埃第三磨牙指数（I3M）的临界值在评估法定成年年龄（18岁）时的准确性。为此，分析了286名年龄在15至22岁之间的在世受试者（152名女性和134名男性）的曲面断层片（OPT）样本。I3M的评估者内和评估者间一致性分别为0.998和0.998，评估者内和评估者间在判定成年人或未成年人方面的科恩卡帕系数分别为1.0和1.0。在男性和女性中，随着I3M的增加，年龄分布逐渐降低。当I3M在0.04至0.08之间时，女性的平均年龄高于男性。男性的敏感性测试为94.1%，95%置信区间（95%CI）为85.6 - 98.4%，特异性为90.9%（95%CI 81.3 - 96.6%）。正确分类个体的比例为92.5%，95%CI为（86.7%，96.4%）。对于女性，敏感性测试为75.4%，95%CI为（63.1%，85.2%），特异性为96.6%，95%CI为（90.3%，99.3%）。正确分类个体的比例为87.5%，95%CI为（81.2%，92.3%）。结果表明，卡梅里埃第三磨牙指数的临界值（I3M = 0.08）有助于区分阿尔巴尼亚的成年人和青少年，并促使我们测试其在确定其他人群个体成年年龄方面的适用性。
