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早期直肠癌的脉络膜转移:病例报告及文献综述

Choroidal metastasis from early rectal cancer: Case report and literature review.

作者信息

Tei Mitsuyoshi, Wakasugi Masaki, Akamatsu Hiroki

机构信息

Department of Surgery, Osaka Police Hospital, 10-31, Kitayama-cho, Tennoji-ku, Osaka City, Osaka 543-0035, Japan.

Department of Surgery, Osaka Police Hospital, 10-31, Kitayama-cho, Tennoji-ku, Osaka City, Osaka 543-0035, Japan.

出版信息

Int J Surg Case Rep. 2014;5(12):1278-81. doi: 10.1016/j.ijscr.2014.10.059. Epub 2014 Nov 4.

Abstract

INTRODUCTION

Choroidal metastasis from colorectal cancer is rare, and there have been no reported cases of such metastasis from early colorectal cancer. We report a case of choroidal metastasis from early rectal cancer.

PRESENTATION OF CASE

A 61 year-old-man experienced myodesopsia in the left eye 2 years and 6 months after primary rectal surgery for early cancer, and was diagnosed with left choroidal metastasis and multiple lung metastases. Radiotherapy was initiated for the left eye and systemic chemotherapy is initiated for the multiple lung metastases. The patient is living 2 years and 3 months after the diagnosis of choroidal metastasis without signs of recurrence in the left eye, and continues to receive systemic chemotherapy for multiple lung metastases.

DISCUSSION

Current literatures have few recommendations regarding the appropriate treatment of choroidal metastasis from colorectal cancer, but an aggressive multi-disciplinary approach may be effective in local regression.

CONCLUSION

This is the first report of choroidal metastasis from early rectal cancer. We consider it important to enforce systemic chemotherapy in addition to radiotherapy for choroidal metastasis from colorectal cancer.

摘要

引言

结直肠癌的脉络膜转移罕见,早期结直肠癌发生此类转移尚无病例报道。我们报告一例早期直肠癌脉络膜转移病例。

病例介绍

一名61岁男性在早期直肠癌初次直肠手术后2年零6个月出现左眼飞蚊症,被诊断为左脉络膜转移和多发肺转移。对左眼开始放疗,对多发肺转移开始全身化疗。该患者在脉络膜转移诊断后存活2年零3个月,左眼无复发迹象,并继续接受针对多发肺转移的全身化疗。

讨论

目前文献对于结直肠癌脉络膜转移的适当治疗几乎没有建议,但积极的多学科方法可能对局部消退有效。

结论

这是早期直肠癌脉络膜转移的首例报告。我们认为,除放疗外,对结直肠癌脉络膜转移实施全身化疗很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e23e/4276086/0987d7717df2/gr1.jpg

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