结直肠癌所致转移性眼内肿瘤：病例报告及文献复习
Metastatic Intraocular Tumor Due to Colorectal Adenocarcinoma: Case Report and Literature Review.
作者信息
Cruzado-Sanchez Deivy, Saavedra-Mejia Luis A, Tellez Walter A, Maquera-Torres Grissnery, Serpa-Frias Solon
机构信息
Ophthalmic Oncology Service, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Sociedad Científica de Estudiantes de Medicina Villarrealinos, Universidad Nacional Federico Villarreal, Lima, Peru.
出版信息
J Ophthalmic Vis Res. 2020 Oct 25;15(4):565-570. doi: 10.18502/jovr.v15i4.7794. eCollection 2020 Oct-Dec.
PURPOSE
To describe the clinical and histopathological findings of a case of intraocular metastasis due to colorectal adenocarcinoma and to carry out a literature review.
CASE REPORT
A 64-year-old man with a history of tumor resection due to infiltrating colorectal adenocarcinoma three years previously sought ophthalmological care because of severe ocular pain without response to medical treatment and progressive vision loss in the left eye. On ultrasonographic examination, there was a heterogeneous intraocular choroidal tumor, which occupied approximately 40% of the vitreous cavity, as well as peritumoral serous retinal detachment. The patient underwent left eyeball enucleation. The histopathological diagnosis was metastatic tubular adenocarcinoma involving the retina and choroid that partially infiltrated the sclera and the proximal optic nerve.
CONCLUSION
The present case highlights a rare pathological entity associated with variable therapeutic schemes and survival times and poor prognosis in patients with metastatic intraocular tumors due to colorectal adenocarcinoma.
目的
描述一例因结直肠癌发生眼内转移的临床及组织病理学表现，并进行文献复习。
病例报告
一名64岁男性，3年前因浸润性结直肠癌行肿瘤切除术，因左眼剧烈眼痛且药物治疗无效、视力进行性下降而寻求眼科治疗。超声检查显示，眼内脉络膜肿瘤不均匀，占据玻璃体腔约40%，并伴有肿瘤周围浆液性视网膜脱离。患者接受了左眼眼球摘除术。组织病理学诊断为转移性管状腺癌，累及视网膜和脉络膜，部分浸润巩膜和近端视神经。
结论
本病例突出了一种罕见的病理实体，其与转移性眼内肿瘤患者的不同治疗方案、生存时间及预后不良相关，该转移性眼内肿瘤由结直肠癌引起。
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